Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Ep. 142: Papers of the Month: Mismatch Repair & DNA Expansion in Huntington’s Disease

Moderator: Jean-Marc Burgunder (Guemligen, Switzerland)Guest: Sandrine Humbert (Paris, France)In this week's episode, Burgunder and Humbert discuss the intriguing phenomenon of somatic expansion—the further increase of CAG repeat numbers in the gene involved in Huntington’s disease, particularly in the striatum. They explore the molecular mechanisms behind this process, as addressed in two recent research papers.Please find here the papers discussed in this episode: Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s diseaseand Distinct mismatch-repair complex genes set neuronal CAG-repeat expansion rate to drive selective pathogenesis in HD mice.eanCampus access for Associate Members: If you are a member of a National Neurological Society in Europe, you are most likely aleady an Associate Member of the EAN and have an account for the eanCampus. If you have provided your email address to your National Neurological Society, it should already be in our database. Here is how you can access the eanCampus as an Associate Member:1. Enter the eanCampus2. Click on the Log In Button3. Log in with your MyEAN credentials and make use of the ‘forgot password’-functionality if necessaryIf you have trouble logging in, please get in contact with our Membership department (membership@ean.org) to cross-check if you are listed as an Associate Member to get access to eanCampus.

Episoder(191)

Ep. 135: Cannabis based medicine in neurology

Ep. 135: Cannabis based medicine in neurology

Moderator: Yıldız Değirmenci (Istanbul, Türkiye) Guest: Natalia Szejko (Warsaw, Poland) In this episode Yıldız Değirmenci interviews Natalia Szejko about the controversial topic of cannabis-based med...

16 Feb 202526min

Ep. 134: Recognizing autoinflammatory syndromes as a neurologist

Ep. 134: Recognizing autoinflammatory syndromes as a neurologist

Moderator: João Moura (Porto, Portugal) Guest: Jeroen Kerstens (Edegem, Belgium) In this episode João Moura and Jeroen Kerstens focus on autoinflammatory syndromes. They discuss how to diagnose them...

9 Feb 202520min

Ep. 133: Autoimmune encephalitis

Ep. 133: Autoimmune encephalitis

EAN moderator: Maria Pia Giannoccaro (Bologna, Italy) Guests: Alberto Vogrig (Udine, Italy), Maarten Titulaer (Rotterdam, The Netherlands) In this first episode of the Neuroimmunology series, Maria ...

2 Feb 202531min

Ep. 132: Paper reviews on post-pandemic neurology risks and ischemic stroke care guidelines

Ep. 132: Paper reviews on post-pandemic neurology risks and ischemic stroke care guidelines

Moderator: Prof. José Ferro (Lisbon, Portugal) Guests: Saša Filipović (Belgrade, Serbia), Charlotte Lens (Leuven, Belgium) In this episode, first, join Ferro and Filipović as they discuss updated co...

26 Jan 202527min

Ep. 131: Assessment of prognosis in TBI

Ep. 131: Assessment of prognosis in TBI

Moderator: Luca Sebastianelli (Vipiteno, Italy) Guest: Olli Tenovuo (Turku, Finland) In this episode Luca Sebastianelli and Olli Tenovuo discuss the many factors that influence the recovery and thus...

19 Jan 202526min

Ep. 130: The juvenile brain

Ep. 130: The juvenile brain

EAN Moderator: Jana Midelfart Hoff (Bergen, Norway) Guest: Marte Roa Syversen (Drammen, Norway) In this week’s episode Jana Midelfart Hoff and Marte Roa Syversen discuss what happens in the brain w...

12 Jan 202526min

Ep. 129: From then to now: Neurology through the years

Ep. 129: From then to now: Neurology through the years

EAN moderator: Thomas Berger (Vienna, Austria) Guest: Gereon Fink (Cologne, Germany) In this first eanCast episode of 2025, Thomas Berger and Gereon Fink discuss how dramatically Neurology has chang...

5 Jan 202532min

Ep. 128: Inclusive Communication with sexual and gender minorities in Neurology

Ep. 128: Inclusive Communication with sexual and gender minorities in Neurology

Moderator: Francesco Pasini (Milano, Italy) Cianán Russell (Brussels, Belgium) In this last episode of the year, Francesco Pasini and Cianán Russel talk about inclusive communication with sexual and...

29 Des 202422min

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