313 | Eric Topol on the Changing Face of Medicine and Aging

313 | Eric Topol on the Changing Face of Medicine and Aging

Medical science is advancing at an astonishing rate. Today we talk with leading expert Eric Topol about two aspects of this story. First, the use of artificial intelligence in medicine, especially in diagnostics. This is an area that is a perfect match between an important question and the capabilities of machine learning, to the point where AI can out-perform human doctors. And second, our understanding of aging and what to do about it. Eric even gives some actionable advice on how to live more healthily into our golden years.

Blog post with transcript: https://www.preposterousuniverse.com/podcast/2025/05/05/episode-313-eric-topol-on-the-changing-face-of-medicine-and-aging/

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Eric Topol received and M.D. from the University of Rochester. He is currently the Gary and Mary West Chair of Innovative Medicine in the Department of Translational Medicine at Scripps Research. He is also the Founder, Scripps Research Translational Institute, and Senior Consultant, Scripps Clinic, Division of Cardiovascular Diseases. Among his awards are the Hutchinson Medal from the University of Rochester and membership in the National Academy of Sciences. His books include Deep Medicine: How Artificial Intelligence Can Make Healthcare Human Again, and Super Agers: An Evidence-Based Approach to Longevity.


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Episoder(398)

140 | Dean Buonomano on Time, Reality, and the Brain

140 | Dean Buonomano on Time, Reality, and the Brain

“Time” and “the brain” are two of those things that are somewhat mysterious, but it would be hard for us to live without. So just imagine how much fun it is to bring them together. Dean Buonomano is one of the leading neuroscientists studying how our brains perceive time, which is part of the bigger issue of how we construct models of the physical world around us. We talk about how the brain tells time very differently than the clocks that we’re used to, using different neuronal mechanisms for different timescales. This brings us to a very interesting conversation about the nature of time itself — Dean is a presentist, who believes that only the current moment qualifies as “real,” but we don’t hold that against him.Support Mindscape on Patreon.Dean Buonomano received his Ph.D. from the Department of Neurobiology and Anatomy at the University of Texas Medical School, Houston. He is currently a Professor in the Department of Neurobiology at UCLA. His lab studies how the brain perceives time and constructs models of the external physical world. He is the author of Brain Bugs: How the Brain’s Flaws Shape our Lives and Your Brain is a Time Machine: The Neuroscience and Physics of Time.Lab web siteUCLA web pageGoogle Scholar publicationsAmazon.com author pageWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Mar 20211h 27min

139 | Elizabeth Anderson on Equality, Work, and Ideology

139 | Elizabeth Anderson on Equality, Work, and Ideology

Imagine two people with exactly the same innate abilities, but one is born into a wealthy family and the other is born into poverty. Or two people born into similar circumstances, but one is paralyzed in a freak accident in childhood while the other grows up in perfect health. Is this fair? We live in a society that values some kind of “equality” — “All men are created equal” — without ever quite specifying what we mean. Elizabeth Anderson is a leading philosopher of equality, and we talk about what really matters about this notion. This leads to down-to-earth issues about employment and the work ethic, and how it all ties into modern capitalism. We end up agreeing that a leisure society would be great, but at the moment there’s plenty of work to be done.Support Mindscape on Patreon.Elizabeth Anderson received a Ph.D. in philosophy from Harvard University. She is currently the Arthur F. Thurnau Professor and John Dewey Distinguished University Professor of Philosophy and Women’s Studies at the University of Michigan. Among her honors are the MacArthur Fellowship, a Guggenheim Fellowship, and membership in the American Academy of Arts and Sciences. She was named by Prospect magazine as one of the top 50 thinkers of the Covid-19 era.Web siteUniversity of Michigan web pageNew Yorker profileAmazon.com author pageGoogle Scholar publicationsWikipediaSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Mar 20211h 19min

138 | Daryl Morey on Analytics, Psychology, and Basketball

138 | Daryl Morey on Analytics, Psychology, and Basketball

You might think that human beings, exhausted by competing for resources and rewards in the real world, would take it easy and stick to cooperation in their spare time. But no; we are fascinated by competition, and invent games and sports to create artificial competition just for fun. These competitions turn out to be wonderful laboratories for exploring concepts like optimization, resource allocation, strategy, and human psychology. Today’s guest, Daryl Morey, is a world leader in thinking analytically about sports, as well as the relationship between impersonal data and the vagaries of human behavior. He’s currently an executive in charge of the Philadelphia 76ers, but I promise you don’t need to be a fan of the Sixers or of basketball or of sports in general to enjoy this wide-ranging conversation.Support Mindscape on Patreon.Daryl Morey received a bachelor’s in computer science from Northwestern University, and an MBA from the MIT Sloan School of Management. He served as general manager for the Houston Rockets from 2007 to 2020, and since November 2020 has been the President for Basketball Operations for the Philadelphia 76ers. He is founder and co-chair of the annual MIT Sloan Sports Analytics Conference. He was voted NBA Executive of the Year in 2018.Philadelphia 76ersBasketball-Reference pageWikipediaTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Mar 20211h 16min

AMA | March 2021

AMA | March 2021

Welcome to the March 2021 Ask Me Anything episode of Mindscape! These are funded by Patreon supporters (who are also the ones asking the questions). With an expanding number of questions, it’s become a bit impractical for me to try to rush through and answer them all. So instead, this time I have picked out certain questions to tackle, and grouped some together if they were related. I tried to pick questions on the basis of whether or not I had anything interesting to say in response, but that will of course be in the ear of the listener.Support Mindscape on Patreon.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Mar 20213h 11min

137 | Justin Clarke-Doane on Mathematics, Morality, Objectivity, and Reality

137 | Justin Clarke-Doane on Mathematics, Morality, Objectivity, and Reality

On a spectrum of philosophical topics, one might be tempted to put mathematics and morality on opposite ends. Math is one of the most pristine and rigorously-developed areas of human thought, while morality is notoriously contentious and resistant to consensus. But the more you dig into the depths, the more alike these two fields appear to be. Justin Clarke-Doane argues that they are very much alike indeed, especially when it comes to questions of “reality” and “objectivity” — but that they aren’t quite exactly analogous. We get a little bit into the weeds, but this is a case where close attention will pay off.Support Mindscape on Patreon.Justin Clarke-Doane received his Ph.D. in philosophy from New York University. He is currently Associate Professor of philosophy at Columbia University, as well as an Honorary Research Fellow at the University of Birmingham and Adjunct Research Associate at Monash University. His book Morality and Mathematics was published in 2020.Web siteColumbia web pageGoogle Scholar publicationsInterview at What Is It Like to Be a Philosopher?Heyman Center eventSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

8 Mar 20211h 32min

136 | Roderick Graham on Cyberspace, Race, and Cultural Conservatism

136 | Roderick Graham on Cyberspace, Race, and Cultural Conservatism

The internet has made it so much easier for people to talk to each other, in a literal sense. But it hasn’t necessarily made it easier to have rewarding, productive, good-faith conversations. Here I talk with sociologist Rod Graham about what kinds of conversations the internet does enable, and should enable, and how we can work to make them better. We discuss both how social media are used for nefarious purposes, from cyberbullying to driving extremism, but also how they can be mobilized for more lofty goals. We also get into some of the lost nuances in conventional discussions of race, including how many minorities are more culturally conservative than an oversimplified narrative would lead us to believe, and the tricky relationship between online discourse and social cohesion.Support Mindscape on Patreon.Roderick Graham received his Ph.D. in sociology from the City University of New York. He is currently an Associate Professor of Sociology and Criminal Justice at Old Dominion University, and serves as the coordinator of the university’s Cybercriminology Bachelor’s program. He is the author of The Digital Practices of African-Americans.Web siteOld Dominion web pageGoogle Scholar publicationsArticles on MediumYouTube channelTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Mar 20211h 23min

135 | Shadi Bartsch on Plato, Vergil, Confucius, and Modernity

135 | Shadi Bartsch on Plato, Vergil, Confucius, and Modernity

In our postmodern world, studying the classics of ancient Greece and Rome can seem quaint at best, downright repressive at worst. (We are talking about works by dead white men, after all.) Do we still have things to learn from classical philosophy, drama, and poetry? Shadi Bartsch offers a vigorous affirmative to this question in two new books coming from different directions. First, she has newly translated the Aeneid, Vergil’s epic poem about the founding myth of Rome, bringing its themes into conversation with the modern era. Second, in the upcoming Plato Goes to China, she explores how a non-Western society interprets classic works of Western philosophy, and what that tells us about each culture.Support Mindscape on Patreon.Shadi Bartsch-Zimmer received her Ph.D. in Classics from the University of California, Berkeley. She is currently the Helen A. Regenstein Distinguished Service Professor of Classics at the University of Chicago. Among her awards are a Guggenheim Fellowship, an American Council of Learned Societies Fellowship, and multiple teaching awards. She has served as the Editor-in-Chief of Classical Philology, and is the Founding Director of the Stevanovich Institute on the Formation of Knowledge. She is developing an upcoming podcast.Web siteUniversity of Chicago web pageWikipediaTwitterAmazon author pageWashington Post Op-EdSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Feb 20211h 20min

AMA | February 2021

AMA | February 2021

Welcome to the February 2021 Ask Me Anything episode of Mindscape! These are funded by Patreon supporters (who are also the ones asking the questions). This month is in what has been the conventional format, where I just try my best to answer every question. But it’s growing a bit unwieldy, so going forward I might just try to pick my favorite questions and answer them in greater detail. We shall see.Support Mindscape on Patreon.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Feb 20212h 53min

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