#526: Building Data Science with Foundation LLM Models
Today, we’re talking about building real AI products with foundation models. Not toy demos, not vibes. We’ll get into the boring dashboards that save launches, evals that change your mind, and the shi...
1 Nov 20251h 7min
#525: NiceGUI Goes 3.0
Building a UI in Python usually means choosing between "quick and limited" or "powerful and painful." What if you could write modern, component-based web apps in pure Python and still keep full contro...
27 Okt 20251h 17min
#524: 38 things Python developers should learn in 2025
Python in 2025 is different. Threads really are about to run in parallel, installs finish before your coffee cools, and containers are the default. In this episode, we count down 38 things to learn th...
20 Okt 20251h 9min
#523: Pyrefly: Fast, IDE-friendly typing for Python
Python typing got fast enough to feel invisible. Pyrefly is a new, open source type checker and IDE language server from Meta, written in Rust, with a focus on instant feedback and real-world DX. Toda...
13 Okt 20251h 7min
#522: Data Sci Tips and Tricks from CodeCut.ai
Today we’re turning tiny tips into big wins. Khuyen Tran, creator of CodeCut.ai, has shipped hundreds of bite-size Python and data science snippets across four years. We dig into open-source tools you...
6 Okt 20251h 9min
#521: Red Teaming LLMs and GenAI with PyRIT
English is now an API. Our apps read untrusted text; they follow instructions hidden in plain sight, and sometimes they turn that text into action. If you connect a model to tools or let it read docum...
29 Sep 20251h 2min
#520: pyx - the other side of the uv coin (announcing pyx)
A couple years ago, Charlie Marsh lit a fire under Python tooling with Ruff and then uv. Today he’s back with something on the other side of that coin: pyx. Pyx isn’t a PyPI replacement. Think server...
23 Sep 20251h
#519: Data Science Cloud Lessons at Scale
Today on Talk Python: What really happens when your data work outgrows your laptop. Matthew Rocklin, creator of Dask and cofounder of Coiled, and Nat Tabris a staff software engineer at Coiled join me...
18 Sep 20251h 2min
