Epigenetic Medicine with Laura Hsieh of TippingPoint Biosciences

Epigenetic Medicine with Laura Hsieh of TippingPoint Biosciences

Laura Hsieh is the founder of TippingPoint Biosciences, an epigenetic medicine startup that has developed a breakthrough method of drugging the entire chromatin network to create first-in-class epigenetic therapeutics. Laura sits down with Sam Tabone and Brom Rector to discuss:


(1:11) Laura’s background and the history of TippingPoint


(5:30) What is Epigenetics and what is Chromatin?


(10:30) What diseases are driven by Epigenetics and dysfunctional Chromatin?


(14:00) - TippingPoint’s platform and secret sauce


(19:10) - How TippingPoint runs high throughput screening


(23:00) - What is DIPG - the deadly pediatric brain cancer TippingPoint is treating?


(38:30) - What does “disease modifying” mean?


(40:00) - How TippingPoint’s technology can be applied to aging and longevity


(45:00) - What motivates Laura


(49:00) - Could epigenetic medicines be used for human enhancement? How does diet influence Epigenetics?


(55:00) - Academia vs the startup world: does the PhD experience prepare you to be a founder?


(59:00) - Laura’s advice for raising money and pitching VCs

(1:04:00) - Why we invested in TippingPoint


Check out TippingPoint: https://www.tippingpointbiosciences.com/

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