198 | Nick Lane on Powering Biology

The origin of life here on Earth was an important and fascinating event, but it was also a long time ago and hasn't left many pieces of direct evidence concerning what actually happened. One set of clues we have comes from processes in current living organisms, especially those processes that seem extremely common. The Krebs cycle, the sequence of reactions that functions as a pathway for energy distribution in aerobic organisms, is such an example. I talk with biochemist about the importance of the Krebs cycle to contemporary biology, as well as its possible significance in understanding the origin of life.

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Nick Lane received his PhD from the Royal Free Hospital Medical School. He is currently a professor of Evolutionary Biochemistry at University College London. He was a founding member of the UCL Consortium for Mitochondrial Research, and is Co-Director of the UCL Centre for Life's Origin and Evolution. He was awarded the 2009 UCL Provost's Venture Research Prize, the 2011 BMC Research Award for Genetics, Genomics, Bioinformatics and Evolution, the 2015 Biochemical Society Award, and the 2016 Royal Society Michael Faraday Prize and Lecture. His new book is Transformer: The Deep Chemistry of Life and Death.


Episoder(424)

85 | L.A. Paul on Transformative Experiences and Your Future Selves

85 | L.A. Paul on Transformative Experiences and Your Future Selves

It's hard to make decisions that will change your life. It's even harder to make a decision if you know that the outcome could change who you are. Our preferences are determined by who we are, and the...

24 Feb 20201h 14min

84 | Suresh Naidu on Capitalism, Monopsony, and Inequality

84 | Suresh Naidu on Capitalism, Monopsony, and Inequality

Nations generally want their economies to be rich, robust, and growing. But it's also important to person to ensure that wealth doesn't flow only to a few people, but rather that as many people as pos...

17 Feb 20201h 26min

83 | Kwame Anthony Appiah on Identity, Stories, and Cosmopolitanism

83 | Kwame Anthony Appiah on Identity, Stories, and Cosmopolitanism

The Greek statesman Demosthenes is credited with saying "I am a citizen of the world," and the idea that we should take a cosmopolitan view of our common humanity is a compelling one. Not everyone agr...

10 Feb 20201h 38min

82 | Robin Carhart-Harris on Psychedelics and the Brain

82 | Robin Carhart-Harris on Psychedelics and the Brain

The Convention on Psychotropic Substances was a 1971 United Nations treaty that placed strong restrictions on the use of psychedelic drugs — not only on personal use, but medical and scientific resear...

3 Feb 20201h 17min

81 | Ezra Klein on Politics, Polarization, and Identity

81 | Ezra Klein on Politics, Polarization, and Identity

People have always disagreed about politics, passionately and sometimes even violently. But in certain historical moments these disagreements were distributed without strong correlations, so that any ...

27 Jan 20201h 21min

80 | Jenann Ismael on Connecting Physics to the World of Experience

80 | Jenann Ismael on Connecting Physics to the World of Experience

Physics is simple; people are complicated. But even people are ultimately physical systems, made of particles and forces that follow the rules of the Core Theory. How do we bridge the gap from one kin...

20 Jan 20201h 26min

79 | Sara Imari Walker on Information and the Origin of Life

79 | Sara Imari Walker on Information and the Origin of Life

We are all alive, but "life" is something we struggle to understand. How do we distinguish a "living organism" from an emergent dynamical system like a hurricane, or a resource-consuming chemical reac...

13 Jan 20201h 23min

78 | Daniel Dennett on Minds, Patterns, and the Scientific Image

78 | Daniel Dennett on Minds, Patterns, and the Scientific Image

Wilfrid Sellars described the task of philosophy as explaining how things, in the broadest sense of term, hang together, in the broadest sense of the term. (Substitute "exploring" for "explaining" and...

6 Jan 20202h 1min

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