Essentials: Understanding & Treating Addiction | Dr. Anna Lembke
Huberman Lab26 Jun 2025

Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine. We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Wealthfront**: https://wealthfront.com/huberman BetterHelp: https://betterhelp.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Anna Lembke 00:00:15 Dopamine, Reward & Movement 00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction 00:05:24 Addiction, Modern Life & Boredom 00:07:18 Sponsor: AG1 00:08:55 Pleasure-Pain Balance, Dopamine, Addiction 00:14:17 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence 00:16:04 Relapse, Addiction, Reflexive Behavior, Empathy 00:20:17 Triggers, Relapse, Dopamine 00:23:15 Sponsor: Wealthfront & BetterHelp 00:26:04 Shame, Truth Telling & Recovery 00:28:26 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA 00:33:29 Social Media & Addiction, Tool: Intentionality Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(376)

Control Your Vagus Nerve to Improve Mood, Alertness & Neuroplasticity

Control Your Vagus Nerve to Improve Mood, Alertness & Neuroplasticity

In this episode I explain how your vagus nerve—an extensive neural pathway linking your brain and body in both directions—powerfully regulates your mood, digestion, alertness and even certain food cra...

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Essentials: How to Control Your Sense of Pain & Pleasure

Essentials: How to Control Your Sense of Pain & Pleasure

In this Huberman Lab Essentials episode, I explore the sensations of pain and pleasure, explaining how they are sensed in the body and interpreted by the brain as well as methods to control their inte...

19 Jun 202537min

How to Grow From Doing Hard Things | Michael Easter

How to Grow From Doing Hard Things | Michael Easter

My guest is Michael Easter, a professor at the University of Nevada, Las Vegas and best-selling author. We discuss how particular daily life choices undermine our level of joy, our sense of purpose, o...

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Essentials: The Science & Practice of Perfecting Your Sleep

Essentials: The Science & Practice of Perfecting Your Sleep

In this Huberman Lab Essentials episode my guest is Dr. Matt Walker, PhD, Professor of Neuroscience and Psychology at the University of California, Berkeley and host of The Matt Walker Podcast, which ...

12 Jun 202541min

Improving Science & Restoring Trust in Public Health | Dr. Jay Bhattacharya

Improving Science & Restoring Trust in Public Health | Dr. Jay Bhattacharya

My guest is Dr. Jay Bhattacharya, MD, PhD, Director of the National Institutes of Health (NIH) and Professor Emeritus of Health Policy at Stanford University. We discuss which scientific questions oug...

9 Jun 20254h 27min

Essentials: Improving Health With Stronger Brain-Body Connection

Essentials: Improving Health With Stronger Brain-Body Connection

In this Huberman Lab Essentials episode, I discuss interoception, the brain’s ability to sense and interpret signals from the body, which shapes our sense of self and underlies vital functions like fo...

5 Jun 202540min

Healing From Grief & Loss | Dr. Mary-Frances O'Connor

Healing From Grief & Loss | Dr. Mary-Frances O'Connor

My guest is Dr. Mary-Frances O’Connor, PhD, Professor of Clinical Psychology and Psychiatry at the University of Arizona and a world expert on the science of grief and loss. We discuss what happens in...

2 Jun 20252h 34min

Essentials: Machines, Creativity & Love | Dr. Lex Fridman

Essentials: Machines, Creativity & Love | Dr. Lex Fridman

In this Huberman Lab Essentials episode my guest is Lex Fridman, PhD, a research scientist at the Massachusetts Institute of Technology (MIT), an expert in robotics and host of the Lex Fridman Podcast...

29 Mai 202548min

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