The Art of Manliness15 Jul 2025

The Microbiome Master Key — How 100 Trillion Bacteria Influence Your Weight, Mood, and All-Around Health

When you think of the microbiome, you probably think of your gut. But bacteria live all over your body. And they’re incredibly numerous; you play host to about as many microbes — a hundred trillion of them — as you do human cells.

As my guest will explain, these microbial ecosystems are not only ubiquitous but hugely influential for your health — impacting everything from your weight and mood to your risk of developing many diseases.

Dr. Brett Finlay is a microbiologist and the co-author of The Microbiome Master Key. Today on the show, Brett explains what the microbiome is, how modern life — including our overemphasis on hygiene — has damaged it, and how the quality of your microbiome is connected to nine of the top ten leading causes of death, as well as everything from depression to Parkinson’s. Brett also shares how we can boost the health of our microbiome, including whether probiotic supplements are effective, how something as simple as flossing your teeth can cut your risk of Alzheimer’s by 50%, and why you might want to let your dog lick you in the face.

Resources Related to the Podcast

Connect With Brett Finlay

Brett’s faculty page

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