Valproate and reproductive risks in women and men with epilepsy: Dr. Tony Marson

Valproate and reproductive risks in women and men with epilepsy: Dr. Tony Marson

Send comments and feedback In use since the 1970s, valproate is highly effective for genetic generalized epilepsies and some forms of pediatric epilepsy. The medication also is associated with a 10% risk of birth defects in children exposed to it in utero, as well as a 30% to 40% risk of neurodevelopmental issues, including autism. Sharp Waves spoke with Dr. Tony Marson about the reproductive risks for women and men taking valproate, discussing UK policies meant to ensure appropriate prescrip...

Episoder(103)

Genetic testing for epilepsy in low-resource regions

Genetic testing for epilepsy in low-resource regions

Send comments and feedback In lower- and middle-income countries, raising awareness of genetic etiologies in epilepsy and genetic testing options may ultimately shift national priorities toward making...

14 Apr 202524min

Emergency diagnosis and treatment of status epilepticus

Emergency diagnosis and treatment of status epilepticus

Send comments and feedback As a neurological emergency, status epilepticus (SE) requires timely diagnosis and treatment. A US study found that 10% of people with SE were not diagnosed by emergency ser...

31 Mar 202529min

Folic acid supplementation in women with epilepsy

Folic acid supplementation in women with epilepsy

Send comments and feedback Folic acid supplementation is recommended for all women with epilepsy who may become pregnant. However, there is no agreed-upon dose for women with epilepsy taking antiseizu...

17 Mar 202521min

High-frequency oscillations and epilepsy: Clinical and basic science perspectives

High-frequency oscillations and epilepsy: Clinical and basic science perspectives

Send comments and feedback High-frequency oscillations (80 to 500 Hz) are being studied as biomarkers of epileptogenic areas in the brain, as well as markers to be used in epilepsy surgery. Dr. Cecili...

3 Mar 202525min

Finding epilepsy genes: Dr. Allan Bayat

Finding epilepsy genes: Dr. Allan Bayat

Send comments and feedback There are potentially hundreds of "epilepsy genes" - but what is an epilepsy gene? How do researchers discover these genes and associate them with epilepsy? Sharp Waves spok...

17 Feb 202514min

Genetic testing for epilepsy surgery: Dr. Pat Moloney

Genetic testing for epilepsy surgery: Dr. Pat Moloney

Send comments and feedback In the second episode of our genetics and epilepsy series, Sharp Waves explores how genetic insights can inform considerations and outcomes of epilepsy surgery. Dr. Alina Iv...

3 Feb 202523min

Genetic testing in epilepsy: Who, how, and why? Dr. Ilona Krey

Genetic testing in epilepsy: Who, how, and why? Dr. Ilona Krey

Send comments and feedback This first episode in a multipart series on genetics in epilepsy covers the basics of genetic testing. Dr. Alina Ivaniuk interviews Dr. Ilona Krey, a physician and researche...

20 Jan 202516min

Epilepsy surgery outcomes: Two experiences with life-changing consequences

Epilepsy surgery outcomes: Two experiences with life-changing consequences

Send comments and feedback Christina Rezek and Brad Levy each have daughters who underwent epilepsy surgery, with dramatically different results. Sharp Waves talked with them about the journeys to and...

9 Des 202427min

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