#425 — Are We Prepared for the Next Pandemic?
Making Sense with Sam Harris21 Jul 2025

#425 — Are We Prepared for the Next Pandemic?

Sam Harris speaks with Marc Lipsitch about pandemic preparedness. They discuss what we learned from Covid, loss of trust in institutions, how to effectively communicate scientific information in the current media landscape, vaccine hesitancy, the safety of mRNA vaccines, the origins of Covid, gain-of-function research, virus hunting, the Trump administration's assault on scientific research and universities, future pandemic threats, and other topics.

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Learning how to train your mind is the single greatest investment you can make in life. That's why Sam Harris created the Waking Up app. From rational mindfulness practice to lessons on some of life's most important topics, join Sam as he demystifies the practice of meditation and explores the theory behind it.

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Episoder(500)

#486 — Luck All the Way Down

#486 — Luck All the Way Down

Sam Harris speaks with Kathryn Paige Harden about behavioral genetics, moral luck, and the problem of blame. They discuss Harden's book Original Sin, the controversy over Charles Murray and Ezra Klein...

22 Jul 21min

#485 — The New Science of Cancer

#485 — The New Science of Cancer

Sam Harris speaks with Siddhartha Mukherjee about the science of cancer. They discuss the updated edition of The Emperor of All Maladies, whether cancer is one disease or many, why prevention is so ha...

14 Jul 1h 21min

#484 — Artificial Intimacy

#484 — Artificial Intimacy

Sam Harris speaks with Paul Bloom about our relationships with AI and the future of human connection. They discuss the surprising pace of AI progress, AI companions as a remedy for loneliness, the imp...

8 Jul 27min

#483 — The Knots We Tie Ourselves Into

#483 — The Knots We Tie Ourselves Into

Sam Harris speaks with Alain de Botton about the psychology of unhappiness, the secular world's discomfort with ecstasy and ritual, psychedelics as a tool for self-discovery, Freud's legacy, AI as the...

1 Jul 22min

#482 — More From Sam: The Iran Deal, College in the AI Age, Mamdani's DSA, and More

#482 — More From Sam: The Iran Deal, College in the AI Age, Mamdani's DSA, and More

In this latest episode of the More From Sam series, Sam and Jaron talk about current events. They discuss topics from Making Sense Community, including one-world government, the value of a degree as A...

25 Jun 21min

#481 — Sam Harris Receives the 2026 Richard Dawkins Award

#481 — Sam Harris Receives the 2026 Richard Dawkins Award

Richard Dawkins presents Sam Harris with the 2026 Richard Dawkins Award at a live Center for Inquiry event. After the tribute, the two friends discuss consciousness and epiphenomenalism, AI and the Tu...

17 Jun 54min

#480 — The Economics of Everything

#480 — The Economics of Everything

Sam Harris speaks with economist and Substack writer Noah Smith about the U.S. national debt, wealth inequality, and the economic consequences of AI. They discuss the mechanics of debt and inflation, ...

12 Jun 24min

#479 — When Robots Take Over

#479 — When Robots Take Over

Sam Harris speaks with Vinod Khosla about AI, economic disruption, and political risk. They discuss the prospect of mass job displacement, a trillion-dollar policy framework to redistribute AI's gains...

4 Jun 15min

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