Episode 412: Understanding Late-Onset MS with Dr. Jacqueline Nicholas
RealTalk MS21 Jul 2025

Episode 412: Understanding Late-Onset MS with Dr. Jacqueline Nicholas

More people over the age of 50 are being diagnosed with MS than ever before. When you consider the other health conditions that often develop as we age, and you add the fact that our immune system changes with age, there's a lot to think about when it comes to diagnosing and treating late-onset MS.

This week, Dr. Jacqueline Nicholas, the System Chief of Neuroimmunology and Multiple Sclerosis at the OhioHealth Multiple Sclerosis Center, joins me to help us better understand late-onset MS.

We'll also tell you about research results that could lead to a simple blood test that can predict MS years before someone experiences a single symptom.

You'll learn about an ultra-high resolution brain imaging tool that could open the door to precision neuroscience and revolutionize the treatment of neurological disorders

The FDA wants to talk with people about what living with MS is like, and what they're looking for in future treatments. We'll tell you how and where to register for an informational webinar that will give you all the details about the Shaping Tomorrow Together initiative.

And if you're in or around Northern California, we'll remind you that you can join us this Saturday in Napa Valley at Crush MS!

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: Understanding Late-Onset MS :22

How a simple blood test may predict MS years before someone experiences any symptoms 1:34

How a new ultra-high resolution brain imaging tool may revolutionize the treatment of neurological disorders 6:40

Are you interested in telling the FDA what it's like living with MS, and what you want in future treatments? 8:53

Are you ready to support MS research while spending the afternoon in a Napa Valley vineyard? Get all the details to attend Crush MS 10:29

Dr. Jacqueline Nicholas discusses what's different and what's the same in treating late-onset MS 12:09

Share this episode 29:26

Have you downloaded the free RealTalk MS app? 29:46

SHARE THIS EPISODE OF REALTALK MS

Just copy this link & paste it into your text or email: https://realtalkms.com/412

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I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts!

Email: jon@realtalkms.com
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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Become an MS Activist
https://nationalmssociety.org/advocacy

STUDY: Early Identification of Individuals at Risk for Developing Multiple Sclerosis by Quantification of EBNA-1-381-452-Specific Antibody Titers
https://nature.com/articles/s41467-025-61751-9

REGISTER: Informational Webinar on the FDA "Shaping Tomorrow Together" Listening Session
https://nmss.zoom.us/webinar/register/WN_hHdHhEE3TBmPJ2glcgME0Q#/registration

EVENT: Crush MS
https://crushms.org

Join the RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

Download the RealTalk MS App for iOS Devices
https://itunes.apple.com/us/app/realtalk-ms/id1436917200

Download the RealTalk MS App for Android Devices
https://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk

Give RealTalk MS a rating and review
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Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com.

RealTalk MS Episode 412
Guest: Dr. Jacqueline Nicholas

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