Hard: Little Pill, Big Pharma

Hard: Little Pill, Big Pharma

When Dr. Irwin Goldstein started his career in urology in the 1970s, he remembers asking his mentor—an early pioneer in penile implant surgeries—"How the hell does an erection occur in the first place?" His answer: 'We have absolutely no idea,'" Dr. Goldstein recalls. "So I said, okay, well, this is what I'm doing."  In this second episode of our three-part series, Hard, we dive into the medical and scientific advancements that led up to Viagra's FDA approval in 1998. From an unforgettable conference presentation...to an overnight drug study where an unexpected side effect kept popping up...we hear about the strange twists and turns that eventually led to a little blue pill, from some of the people who were there along the way. Plus, we explore the intentionality around the early marketing of Viagra—when former Senate Majority Leader Bob Dole encouraged men to summon the bravery to talk to their doctors—and we hear how that message has shifted over the years. This is the second episode of a three-part series. Listen to the first episode, about the impact of ED and Viagra on relationships, here. And look out for our episode next week, where we meet people for whom Viagra sparked deeper exploration about the meaning of good sex.

Episoder(150)

Hard: Erectile Disappointment

Hard: Erectile Disappointment

Bob first started experiencing erectile dysfunction in his 50s. "The erections wouldn't last," he told me, "and that became kind of a frustration." Bob and his wife, Joanne, tried asking their doctors...

30 Mar 202230min

Why Lynn Nottage Cashed Out Her 401(k)

Why Lynn Nottage Cashed Out Her 401(k)

At the start of this year, two-time Pulitzer Prize winning playwright Lynn Nottage achieved a feat. Three of her works—Clyde's, the musical MJ, and an opera adaptation of her play Intimate Apparel—wer...

16 Mar 202232min

Affairs, Throuples, and Big Monogamy: Your Relationship Questions Answered

Affairs, Throuples, and Big Monogamy: Your Relationship Questions Answered

We recently asked you to tell us about the decisions weighing on you about your romantic lives. The strangeness of the past two years has impacted all of our relationships—in both negative and positiv...

9 Mar 20220s

Inheriting Divorce

Inheriting Divorce

Many of the marriages in producer Ian Coss’ family have ended in divorce. His parents’ marriage, his grandparents’s marriage, as well as some of his aunts and uncles’ marriages. Ian is married, but he...

23 Feb 202231min

Where is Lisa Fischer's Backup?

Where is Lisa Fischer's Backup?

Lisa Fischer has sung backing vocals for Dolly Parton, Bobby McFerrin, Luther Vandross and Beyoncé. She's also toured with the Rolling Stones since 1989, going from one swanky hotel to another, "eatin...

16 Feb 202228min

This Elvis Impersonator Does It For Love… And Money

This Elvis Impersonator Does It For Love… And Money

Brendan Paul never meant to become an Elvis impersonator. He wanted to play in rock bands like Kiss and was an art major in college at UCLA. But one day in his early 20s, he got a haircut—one that lef...

9 Feb 202228min

André De Shields On Living With His Shadow

André De Shields On Living With His Shadow

Self-proclaimed “professional charmer” André De Shields has performed on stage for more than 50 years. Today, at 76 years old, he brings his Tony Award-winning portrayal of Hermes to the Broadway musi...

26 Jan 202235min

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