Hard: Little Pill, Big Pharma

Hard: Little Pill, Big Pharma

When Dr. Irwin Goldstein started his career in urology in the 1970s, he remembers asking his mentor—an early pioneer in penile implant surgeries—"How the hell does an erection occur in the first place?" His answer: 'We have absolutely no idea,'" Dr. Goldstein recalls. "So I said, okay, well, this is what I'm doing."  In this second episode of our three-part series, Hard, we dive into the medical and scientific advancements that led up to Viagra's FDA approval in 1998. From an unforgettable conference presentation...to an overnight drug study where an unexpected side effect kept popping up...we hear about the strange twists and turns that eventually led to a little blue pill, from some of the people who were there along the way. Plus, we explore the intentionality around the early marketing of Viagra—when former Senate Majority Leader Bob Dole encouraged men to summon the bravery to talk to their doctors—and we hear how that message has shifted over the years. This is the second episode of a three-part series. Listen to the first episode, about the impact of ED and Viagra on relationships, here. And look out for our episode next week, where we meet people for whom Viagra sparked deeper exploration about the meaning of good sex.

Episoder(150)

Financial Therapy: A Baby, And A Plan

Financial Therapy: A Baby, And A Plan

In Cora and Garrett's final session with financial therapist Amanda Clayman, they talk about soon becoming parents, and their recent experience consulting a financial advisor while navigating Garrett’...

18 Aug 202140min

Financial Therapy: Struggling To Trust Again

Financial Therapy: Struggling To Trust Again

Financial therapist Amanda Clayman gave a couple we're calling Cora and Garrett an assignment at the end of their first session—talk together about your strengths and weaknesses when it comes to money...

11 Aug 202146min

Financial Therapy: A Secret Gambling Addiction

Financial Therapy: A Secret Gambling Addiction

We first heard from a listener we're calling Cora late last year. "My husband and I recently hit a pretty intense rough patch regarding our financial life, mental health, and the trust in our relation...

4 Aug 202131min

When Grief Doesn't Move In Stages

When Grief Doesn't Move In Stages

Radiolab producer Rachael Cusick's mother died when Rachael was six years old. Her grandmother, Marilyn Ryland, stepped in as a parental figure for Rachael, and while they didn't talk directly about g...

23 Jul 202132min

Doree Shafrir On The Out Of Control IVF Train

Doree Shafrir On The Out Of Control IVF Train

For a long time, writer and podcaster Doree Shafrir didn’t know if she wanted kids. “It wasn’t a future that I fantasized about or necessarily saw myself doing,” she told me. But when Doree entered he...

14 Jul 202141min

When Indie Rockers Become Full-Time Caregivers

When Indie Rockers Become Full-Time Caregivers

In 2010, Johnny Solomon's band, Communist Daughter, was on the rise. But behind the scenes, Johnny was struggling—he was drinking heavily, and abusing meth to the tune of $600 a week. "People see it f...

7 Jul 202128min

A Teen Musician Is Ready For His Solo. His Mom Is Not.

A Teen Musician Is Ready For His Solo. His Mom Is Not.

This week, I speak with Miguel Llapa, who is 18 and just graduating from high school. Miguel is a percussionist, and a soon-to-be college student, with congenital scoliosis — an abnormality of the spi...

23 Jun 202132min

"The Lying Stops Now": Your Hardest Conversations

"The Lying Stops Now": Your Hardest Conversations

Hard conversations often spark a change. Whether they shift something in a relationship, or a situation, or inside you, there is often a definitive "before" and "after" a hard conversation.  When we a...

16 Jun 202127min

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