Hard: Little Pill, Big Pharma

Hard: Little Pill, Big Pharma

When Dr. Irwin Goldstein started his career in urology in the 1970s, he remembers asking his mentor—an early pioneer in penile implant surgeries—"How the hell does an erection occur in the first place?" His answer: 'We have absolutely no idea,'" Dr. Goldstein recalls. "So I said, okay, well, this is what I'm doing."  In this second episode of our three-part series, Hard, we dive into the medical and scientific advancements that led up to Viagra's FDA approval in 1998. From an unforgettable conference presentation...to an overnight drug study where an unexpected side effect kept popping up...we hear about the strange twists and turns that eventually led to a little blue pill, from some of the people who were there along the way. Plus, we explore the intentionality around the early marketing of Viagra—when former Senate Majority Leader Bob Dole encouraged men to summon the bravery to talk to their doctors—and we hear how that message has shifted over the years. This is the second episode of a three-part series. Listen to the first episode, about the impact of ED and Viagra on relationships, here. And look out for our episode next week, where we meet people for whom Viagra sparked deeper exploration about the meaning of good sex.

Episoder(150)

I Love My Dad, But I Don't Love Guns

I Love My Dad, But I Don't Love Guns

Back in the spring, we asked you to tell us about the hardest conversations you've ever had, and the ones you haven't had yet. A listener we're calling Jack wrote in about a conversation he wanted to ...

3 Nov 202134min

Order Up, Tapped Out: Life After Restaurant Burnout

Order Up, Tapped Out: Life After Restaurant Burnout

In the last few months, millions of restaurant and hospitality workers have left their jobs. Right now, there are more job openings in this field than ever before. For many of these workers, the pande...

27 Okt 202137min

Succession's J. Smith-Cameron On Old Haunts and New Normals

Succession's J. Smith-Cameron On Old Haunts and New Normals

A few weeks ago, I was back in New York City for the first time since 2019. It was great—I saw coworkers in person, and I had lunch at one of my old spots, the Waverly Diner, with actor J. Smith-Camer...

20 Okt 202134min

Dead People Don't Have Any Secrets

Dead People Don't Have Any Secrets

Three years into Amanda* and Sam*'s marriage, the couple found out that they were unexpectedly pregnant...with twins. Amanda says she took on the lion's share of the work at home while also juggling a...

6 Okt 202127min

Your Infertility Stories Have Many Different Endings

Your Infertility Stories Have Many Different Endings

Sometimes the path to parenthood isn’t a straight line. What happens when you hit speed bumps on the road to having kids? Earlier this year, I asked you about what happened when you realized becoming ...

29 Sep 202140min

"You Should Be Carrying This. Not Me."

"You Should Be Carrying This. Not Me."

When a listener named Chloe was in college, she says she was sexually assaulted at a party by a former classmate. She filed a police report, but her classmate was never charged with a crime. He left t...

22 Sep 202134min

When A Banker Became A Nun

When A Banker Became A Nun

Sister Josephine Garrett grew up Baptist and worked her way up the corporate ladder—eventually becoming a vice president at Bank of America, where she managed a few hundred employees. But after conver...

8 Sep 202125min

Decision Fatigue Is Real. We Called For Backup.

Decision Fatigue Is Real. We Called For Backup.

We recently asked you to tell us about the decisions you're struggling to make right now. There have been so many choices to make and risks to weigh lately, and after almost 18 months into this pandem...

1 Sep 202159min

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