The Trifecta: EDS, POTs & MCAS
PodcastDX2 Sep 2025

The Trifecta: EDS, POTs & MCAS

What do we mean when we see the word "Trifecta" ?

​In Horse Racing you would be talking about a bet where you must pick the first, second, and third-place horses in the precise order they finish. In skincare, "The Trifecta" can refer to a set of three essential skincare products that work together for visible results, like a cleanser, serum, and moisturizer. But in this show where we discuss healthcare conditions, "medical trifecta" refers to the three specific diseases which are often found to occur together. For today's show that means EDS, (Ehlers Danlos Syndrome) POTs (Postural Orthostatic Tachycardia Syndrome) & MCAS (Mast Cell Activation Syndrome) and our guest is Candace Johnson.

Candace is a mom of three girls and a chronic illness advocate. She shares her journey living with what many of us call "the trifecta": POTS, MCAS, and Ehlers Danlos Syndrome. She also has small fiber neuropathy. Her goal is to bring awareness, especially for people still searching for answers and to remind others they're not alone in this.

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