Reframing Cardiovascular Care | JACC This Week
JACC This Week8 Sep 2025

Reframing Cardiovascular Care | JACC This Week

In this episode, Dr. Harlan Krumholz introduces the September 16, 2025 issue of JACC, which features studies that challenge conventional clinical thinking, including a detailed ECMO physiology study showing that higher ECMO flow does not uniformly raise pulmonary capillary wedge pressure, suggesting the need for individualized management. A novel analysis of the ISCHEMIA trial revealed distinct angina symptom trajectories, emphasizing that recovery is not binary and supporting a more personalized approach to treatment and monitoring. A landmark target trial emulation found that statins significantly reduce cardiovascular risk in patients with type 1 diabetes—filling a key evidence gap. Additional highlights include a call to redefine early cardiogenic shock, a nuanced review of moderate secondary mitral regurgitation, and an editorial reaffirming JACC's commitment to independent, transparent science in alignment with new "Gold Standard Science" principles.

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Episoder(729)

Season 2 Wrap-Up: Thank You, Reflections, and What Comes Next | JACC This Week

Season 2 Wrap-Up: Thank You, Reflections, and What Comes Next | JACC This Week

In this special Season 2 wrap-up of JACC This Week, Dr. Harlan Krumholz and Dr. Carolyn Lam reflect on the pilot season, the energy of ACC.26, and what they've learned from listeners along the way. Fr...

7 Apr 4min

March 31, 2026: Global Cardiovascular Insights & Breakthroughs from China | JACC This Week

March 31, 2026: Global Cardiovascular Insights & Breakthroughs from China | JACC This Week

This week's edition of JACC This Week brings Dr. Carolyn Lam and Dr. Harlan Krumholz into a deep exploration of a special issue devoted to innovative cardiovascular research emerging from China. As th...

31 Mar 19min

March 24, 2026: Cardiometabolic Health, COVID Impact & Prevention Science | JACC This Week

March 24, 2026: Cardiometabolic Health, COVID Impact & Prevention Science | JACC This Week

Drs. Carolyn Lam and Harlan Krumholz unpack new JACC research on cardiometabolic health, highlighting how COVID‑19 shaped cardiovascular care, mortality patterns, and disparities. They also break down...

24 Mar 13min

March 17, 2026: Heart Failure, Chagas Research & AI in Cardiology | JACC This Week

March 17, 2026: Heart Failure, Chagas Research & AI in Cardiology | JACC This Week

In this episode, Dr. Carolyn Lam and Dr. Harlan Krumholz break down key studies from this week's JACC issue, including new evidence on Chagas‑related heart failure, updated diastolic function guidelin...

17 Mar 17min

March 10, 2026: Inside JACC Stats: The State of CV Health in Focus | JACC this Week

March 10, 2026: Inside JACC Stats: The State of CV Health in Focus | JACC this Week

Dr. Carolyn Lam and Dr. Harlan Krumholz sit down with Dr. Rishi Wadhera to unpack the first-ever JACC Cardiovascular Statistics issue. They explore why this annual report matters, the key trends in U....

10 Mar 18min

March 3, 2026: Hypertrophic Cardiomyopathy  in Focus—MAPLE-HCM Trial, Myosin Inhibitors & What Improvement Really Means | JACC This Week

March 3, 2026: Hypertrophic Cardiomyopathy in Focus—MAPLE-HCM Trial, Myosin Inhibitors & What Improvement Really Means | JACC This Week

In this episode of JACC This Week, Dr. Carolyn Lam and Dr. Harlan Krumholz spotlight a mini-focus issue on hypertrophic cardiomyopathy (HCM), a field undergoing rapid transformation. The discussion ce...

3 Mar 18min

February 24, 2026: ACHD Guideline in Focus—From Survival to Stewardship | JACC This Week

February 24, 2026: ACHD Guideline in Focus—From Survival to Stewardship | JACC This Week

In this episode of JACC This Week, Dr. Carolyn Lam and Dr. Harlan Krumholz spotlight the 2025 Adult Congenital Heart Disease (ACHD) Guidelines and explore what they signal for the future of cardiovasc...

24 Feb 13min

JACC This Week Bonus Episode – Women's Cardiovascular Health: From Inclusion to Redesign

JACC This Week Bonus Episode – Women's Cardiovascular Health: From Inclusion to Redesign

This bonus episode continues the conversation from the JACC Women's Cardiovascular Health Issue, moving from science to systems. In this extended discussion, Drs. Carolyn Lam and Harlan Krumholz are j...

17 Feb 14min

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