Sep 30, 2022 This Week in Cardiology Podcast

Sep 30, 2022 This Week in Cardiology Podcast

Pulmonary embolism, coffee, when DOACs don't work, lipoprotein (a), and the marginal benefits of current CV therapy are the topics John Mandrola, MD, discusses in this week's podcast.

This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic

I. Pulmonary Embolism

- Positive Data on Thrombectomy Catheter That Avoids Thrombolytics in Acute PE https://www.medscape.com/viewarticle/981322

- Acute Outcomes for the Full US Cohort of the FLASH Mechanical Thrombectomy Registry in Pulmonary Embolism https://eurointervention.pcronline.com/article/acute-outcomes-for-the-full-us-cohort-of-the-flash-mechanical-thrombectomy-registry-in-pulmonary-embolism

- PEERLESS Study https://clinicaltrials.gov/ct2/show/NCT05111613

- Ultrasound-facilitated, Catheter-directed, Thrombolysis in Intermediate-high Risk Pulmonary Embolism (HI-PEITHO) https://clinicaltrials.gov/ct2/show/NCT04790370

- A Prospective, Single-Arm, Multicenter Trial of Catheter-Directed Mechanical Thrombectomy for Intermediate-Risk Acute Pulmonary Embolism: The FLARE Study https://doi.org/10.1016/j.jcin.2018.12.022

II. Coffee Again

- Coffee Linked to Reduced Cardiovascular Disease and Mortality https://www.medscape.com/viewarticle/981518

Enough With the Coffee Research and Other Distractions https://www.medscape.com/viewarticle/883709

- The impact of coffee subtypes on incident cardiovascular disease, arrhythmias, and mortality: long-term outcomes from the UK Biobank https://doi.org/10.1093/eurjpc/zwac189

III. DOAC and Mechanical Valves

- PROACT Xa Trial of Apixaban With On-X Heart Valve Stopped https://www.medscape.com/viewarticle/981644

- Artivion Follows Recommendation to Stop PROACT Xa Clinical Trial https://investors.artivion.com/news-releases/news-release-details/artivion-follows-recommendation-stop-proact-xa-clinical-trial

- PROACT Xa - A Trial to Determine if Participants With an On-X Aortic Valve Can be Maintained Safely on Apixaban https://clinicaltrials.gov/ct2/show/NCT04142658

- Dabigatran versus Warfarin in Patients with Mechanical Heart Valves https://www.nejm.org/doi/full/10.1056/nejmoa1300615

IV. Lipoprotein(a)

- Aspirin Primary Prevention Benefit in Those With Raised Lp(a)? https://www.medscape.com/viewarticle/981602

- Aspirin for Primary Prevention of Cardiovascular Events in Relation to Lipoprotein(a) Genotypes https://www.jacc.org/doi/full/10.1016/j.jacc.2022.07.027

- A Randomized Trial of Low-Dose Aspirin in the Primary Prevention of Cardiovascular Disease in Women https://www.nejm.org/doi/full/10.1056/nejmoa050613

- Effect of Aspirin on Disability-free Survival in the Healthy Elderly https://www.nejm.org/doi/full/10.1056/NEJMoa1800722

- Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly https://www.nejm.org/doi/full/10.1056/NEJMoa1805819

- Effect of Aspirin on All-Cause Mortality in the Healthy Elderly https://www.nejm.org/doi/full/10.1056/NEJMoa1803955

You may also like:

Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine

The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington

Questions or feedback, please contact: news@medscape.net

Episoder(388)

Feb 5, 2021 This Week in Cardiology Podcast

Feb 5, 2021 This Week in Cardiology Podcast

Carotid screening, AF and alcohol, subcutaneous ICD, and medical education are the topics discussed by John Mandrola, MD, in this week's podcast. To read a partial transcript or to comment http://www.medscape.com/twic Carotid Screening USPSTF Again Recommends Against Carotid Stenosis Screening https://www.medscape.com/viewarticle/945202 Subcutaneous ICD Recall FDA Recalls Subcutaneous-ICD Leads Due to Fracture Risk https://www.medscape.com/viewarticle/945168 Alcohol and AF Alcohol and the Electric Atrium, Part 2: When BAC Exceeds the Legal Limit https://www.medscape.com/viewarticle/945297 Medical Education USMLE Stuns Again: Clinical Skills Test Permanently Ended https://www.medscape.com/viewarticle/944756 You may also like: Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

5 Feb 202120min

Jan 29, 2021 This Week in Cardiology Podcast

Jan 29, 2021 This Week in Cardiology Podcast

AF and COVID-19, microthrombi in COVID-19 autopsies, vericiguat, and POTS are the topics covered by John Mandrola, MD, in this week's podcast. To read a partial transcript or to comment: http://www.medscape.com/twic AF and COVID AF at COVID-19 Admission Predicts Mortality, Demands Vigilance https://www.medscape.com/viewarticle/944802 Microthrombi and COVID Microthrombi, Necrosis Seen in COVID-19 Hearts on Autopsy https://www.medscape.com/viewarticle/944783 Vericiguat FDA Approval Adds Vericiguat (Verquvo) to HF Treatment Options https://www.medscape.com/viewarticle/944434 POTS: Lower-Body Compression Trims Orthostatic Tachycardia in POTS https://www.medscape.com/viewarticle/944791 Postural Orthostatic Tachycardia Syndrome (POTS): A critical assessment https://doi.org/10.1016/j.pcad.2020.03.010 Canadian Cardiovascular Society Position Statement on Postural Orthostatic Tachycardia Syndrome (POTS) and Related Disorders of Chronic Orthostatic Intolerance https://www.onlinecjc.ca/article/S0828-282X(19)31550-8/fulltext#secsectitle0130 You may also like: Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, on Medicine and the Machine https://www.medscape.com/features/public/machine The Bob Harrington Show with Stanford University Chair of Medicine, Robert A. Harrington, MD. https://www.medscape.com/author/bob-harrington Questions or feedback, please contact news@medscape.net

29 Jan 202118min

Jan 22, 2021 This Week in Cardiology Podcast

Jan 22, 2021 This Week in Cardiology Podcast

COVID myocarditis, the Polypill, low-value care, and edge-to-edge tricuspid valve repair are discussed by John Mandrola, MD, in this week's podcast.

22 Jan 202121min

Jan 15, 2021 This Week in Cardiology Podcast

Jan 15, 2021 This Week in Cardiology Podcast

COVID, ACE/ARBs, left atrial appendage closure, SGLT2 inhibitors, and a clue in AF mechanisms are the topics discussed by John Mandrola, MD, in this week's podcast.

15 Jan 202118min

Jan 8, 2021 This Week in Cardiology Podcast

Jan 8, 2021 This Week in Cardiology Podcast

COVID vaccine schedules, trial translation, valve guidelines, and physician harassment on social media are the topics discussed by John Mandrola, MD, in this week's podcast.

8 Jan 202119min

Dec 18, 2020 This Week in Cardiology Podcast

Dec 18, 2020 This Week in Cardiology Podcast

COVID, sacubitril/valsartan and spironolactone in patients with HFpEF, year-end comments are the topics discussed by John Mandrola, MD in this week's podcast.

18 Des 202022min

Dec 11, 2020 This Week in Cardiology Podcast

Dec 11, 2020 This Week in Cardiology Podcast

COVID, the clogged pipe frame of CAD, paclitaxel, and AF performance measures and Goodhart's law are the topics John Mandrola, MD, covers in this week's podcast.

11 Des 202018min

Dec 4, 2020 This Week in Cardiology Podcast

Dec 4, 2020 This Week in Cardiology Podcast

COVID vaccines, tocilizumab, finerenone, type 2 MI care, coronary CTA, and sotagliflozin are the topics discussed by John Mandrola, MD, in this week's podcast.

4 Des 202022min

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