My Thyroid Health: Thyroid, Midlife Hormones + Weight Loss23 Sep 2025

Ep. 226: Why Can’t I Lose Weight With Hypothyroidism?

Have you ever felt like your body is working against you—no matter how much you diet or exercise? You’re not imagining it. In this episode, we uncover what really happens when your thyroid slows down—and why shedding pounds becomes an uphill battle.

We’ll dig into the science behind:

How hypothyroidism drags down your metabolism—even when you’re on treatment
Why insulin resistance and leptin resistance throw off your hunger cues and fat storage systems
What role do things like appetite spikes, water retention, fatigue and joint pain play in stalling weight loss efforts

And most importantly: we’ll map out a realistic path forward. Think beyond calories. We’ll talk about:

What “optimal thyroid treatment” really means—and how getting your hormone levels dialed in can make a big difference
How nutrition, sleep, stress, and movement all become part of the equation
When supplements or medications like GLP-1s may be helpful—and what to watch out for

🎧 If you’re tired of feeling like weight loss is impossible, tune in to this episode! It’s your launch pad to understanding why, and discovering how to finally get unstuck!

LEARN MORE

You can learn more about the topic from Paloma:

Why Is It So Hard to Lose Weight When You’re Hypothyroid?

https://www.palomahealth.com/learn/hard-to-lose-weight-hypothyroidism

ABOUT PALOMA HEALTH

⁠⁠Paloma Health ⁠⁠⁠⁠⁠⁠⁠⁠is an online medical practice focused on treating hypothyroidism, Hashimoto’s, perimenopause, menopause, and hormonal weight gain. From online visits with your provider to easy prescription management and lab orders, we create personalized treatment plans for you.

Become a member⁠, or try our at-home test kit and experience a whole new level of hypothyroid care. Use code PODCAST to save $30 at checkout.

Disclaimer: The $30 discount is only valid for first-time Paloma Health members and test kit users. Coupon must be entered at the time of checkout.

Become a Paloma Member:

https://www.palomahealth.com/pricing-hypothyroidism

Paloma Complete Thyroid Blood Test Kit:

https://www.palomahealth.com/home-thyroid-blood-test-kit

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