#436 — A Crisis of Trust

#436 — A Crisis of Trust

Sam Harris speaks with Michael Osterholm about his new book, The Big One: How We Must Prepare for Future Deadly Pandemics. They discuss the lessons learned from the COVID-19 pandemic, the major mistakes made in the public health response—including lockdowns, school closures, and border policies—the science of airborne versus droplet transmission, the promise and controversy of mRNA vaccines, the reality of vaccine adverse events, the politicization of vaccine hesitancy, and the erosion of scientific institutions like the CDC and HHS under the Trump administration. Looking forward, they explore the characteristics of a future, more deadly pandemic—what Osterholm calls “The Big One”—and what we should be doing to prepare for it.

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Episoder(461)

#429 — The New World Order

#429 — The New World Order

Sam Harris speaks with Anne Applebaum about the erosion of democracy at home and abroad. They discuss the Sudanese civil war and the outside forces involved, America’s retreat from global leadership, the impacts of USAID cuts, gerrymandering, the integrity of U.S. elections, the capitulation of Republican representatives to Trump, tariffs, what a post-Trump world could look like, JD Vance as a potential successor to the MAGA movement, Israel’s actions in Gaza, and other topics. If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

11 Aug 26min

#428 — Political Extremism

#428 — Political Extremism

Sam Harris speaks with Jonah Goldberg about Trump 2.0 and wealth inequality. They discuss the horseshoe theory, illiberalism on the Right and the Left, the fallout of the Trump-Epstein controversy, cracks in Trump’s cult following, the difference between MAGA activists and average republican voters, why the Democrats still haven’t course-corrected, problems with the “abundance agenda,” socialism and economic populism, the pitfalls of the far-left’s approach to solving wealth inequality, Israel’s standing on the world stage, and other topics. If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

7 Aug 27min

#427 — AI Friends & Enemies

#427 — AI Friends & Enemies

Sam Harris speaks with Paul Bloom about AI and current events. They discuss the state of LLMs, the risks and benefits of AI companionship, what it means to attribute consciousness to AI, relationships with AI as a form of psychosis, Trump’s attacks on science and academia, what Trump may be trying to hide in the Epstein files, how damaging Trump’s connections to Epstein might be, MAGA’s obsession with conspiracy theories, questions surrounding Epstein’s death, Paul’s research on revenge, Sam’s falling out with Elon Musk, where things went wrong for Elon, and other topics. If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

25 Jul 23min

#426 — How Bad Is It?

#426 — How Bad Is It?

Sam Harris speaks with David Frum about the current state of American politics. They discuss the extent of Trump’s corruption, his immigration crackdowns, what’s going well under Trump 2.0, Trump’s support for Ukraine and Israel, U.S. foreign policy, nuclear proliferation, Israel’s security and internal political conflicts, perceptions of the war in Gaza, the Trump administration’s professed support for Jews, the fallout of DOGE, Trump’s friendship with Jeffrey Epstein, and other topics. If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

23 Jul 27min

#425 — Are We Prepared for the Next Pandemic?

#425 — Are We Prepared for the Next Pandemic?

Sam Harris speaks with Marc Lipsitch about pandemic preparedness. They discuss what we learned from Covid, loss of trust in institutions, how to effectively communicate scientific information in the current media landscape, vaccine hesitancy, the safety of mRNA vaccines, the origins of Covid, gain-of-function research, virus hunting, the Trump administration’s assault on scientific research and universities, future pandemic threats, and other topics. If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe. Learning how to train your mind is the single greatest investment you can make in life. That’s why Sam Harris created the Waking Up app. From rational mindfulness practice to lessons on some of life’s most important topics, join Sam as he demystifies the practice of meditation and explores the theory behind it.

21 Jul 27min

#424 — "More From Sam": Nazi Grok, ICE, Epstein, Social Media, Rapid Fire Questions

#424 — "More From Sam": Nazi Grok, ICE, Epstein, Social Media, Rapid Fire Questions

In this latest episode of the “More From Sam” series, Sam and Jaron talk about current events and answer some of the questions you all submitted on Substack. They discuss Nazi Grok, immigration, ICE raids, Jeffrey Epstein, how to stay focused in the age of distraction, and rapid fire questions. Produced by Griffin Katz

16 Jul 26min

#423 — “More From Sam”: Democracy, Populism, Wealth Inequality, News-Induced Anxiety, & Rapid Fire Questions

#423 — “More From Sam”: Democracy, Populism, Wealth Inequality, News-Induced Anxiety, & Rapid Fire Questions

In this latest episode of the “More From Sam” series, Sam and Jaron talk about current events and answer some of the questions you all submitted on Substack. They discuss Epstein’s “client list,” how to safeguard democracy, populism, wealth inequality, the allure of socialism, how to manage feeling overwhelmed by current events, and rapid fire questions. Produced by Griffin Katz

8 Jul 19min

#422 — Zionism & Jihadism

#422 — Zionism & Jihadism

Sam Harris speaks with Haviv Rettig Gur about Israel and her enemies. They discuss Israel’s war with Iran and America’s role in the conflict, Israel’s military capabilities, Iran’s nuclear program, what a ground invasion of Iran could look like, how Iranians view the regime, antisemitism, the history of Zionism, Islam and jihadism, extremism on the Israeli far right, religious fanaticism, Israeli settlements in the West Bank, Ehud Olmert, the hostages in Gaza, and other topics. If the Making Sense podcast logo in your player is BLACK, you can SUBSCRIBE to gain access to all full-length episodes at samharris.org/subscribe.

19 Jun 2h 4min

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