The GP Show7 Okt 2019

#91 Nutrition, pathophysiology of DMT2, the environment and ending the diet wars

This episode is to supplement my interview with Dr David Unwin and is just with me reviewing and discussing some areas in more detail that David and I ran out of time to cover, including:

Pathophysiology of DMT2 and different dietary considerations
Environmental and farming practices
Ending the Diet Wars

Some further reading for those that want it:

Environmental considerations: https://www.lifestylemedicine.org.au/content/is-the-path-to-health-the-same-path-to-environmental-sustainability/

Nutrition: Principles Before Position Part 3: The externalities of our food choices https://thegpshow.com/musings/pntpart3/

University of Oxford Grazed and Confused report: https://www.oxfordmartin.ox.ac.uk/downloads/reports/fcrn_gnc_report.pdf

UK Sustainable Food Trust: https://sustainablefoodtrust.org/articles/grazed-and-confused-an-initial-response-from-the-sustainable-food-trust/

EAT Lancet: https://eatforum.org/ and https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(20)30055-3/fulltext

2019 Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report from the American Diabetes Association https://care.diabetesjournals.org/content/diacare/early/2019/04/10/dci19-0014.full.pdf

Diabetes Australia position statement on low carb approaches https://static.diabetesaustralia.com.au/s/fileassets/diabetes-australia/dbd70857-a834-45b0-b6f1-ea2582bbe5c7.pdf

Metabolic ward studies/randomised controlled feeding studies on various dietary composition:

https://www.ncbi.nlm.nih.gov/pubmed/29844096

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951141/

Other paper on dietary composition: https://jim.bmj.com/content/65/8/1102

Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes https://diabetes.diabetesjournals.org/content/53/suppl_3/S16

Combination of saturated fats with high GI carbs causing further disease that saturated fats alone in "Saturated fat, carbohydrates and cardiovascular disease", 2011 https://www.ncbi.nlm.nih.gov/pubmed/21978979

Insulinogenic response of foods https://www.ncbi.nlm.nih.gov/pubmed/9356547

Personalized Nutrition by Prediction of Glycemic Responses https://www.ncbi.nlm.nih.gov/pubmed/26590418

Dietary carbohydrate intake and mortality: a prospective cohort study and meta-analysis (observational) https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30135-X/fulltext

High/low animal protein diets and CVD:

https://www.ncbi.nlm.nih.gov/pubmed/11108325

Dr Ornish Lifestyle Heart Disease Reversal study https://www.ncbi.nlm.nih.gov/pubmed/9863851

Other potentials for low carb approaches:

The Therapeutic Potential of Ketogenic Diet Throughout Life: Focus on Metabolic, Neurodevelopmental and Neurodegenerative Disorders, 2019, Professor Sarnyai et al https://www.ncbi.nlm.nih.gov/pubmed/31493223

Adherence to diets:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302176/

https://pubmed.ncbi.nlm.nih.gov/29522789/

https://www.mdpi.com/2072-6643/12/5/1251

Enjoy friends

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