Episode 424: I'm a Participant in a Clinical Trial for CAR-T Cell Therapy and MS with Jan Janisch-Hanzlik
RealTalk MS13 Okt 2025

Episode 424: I'm a Participant in a Clinical Trial for CAR-T Cell Therapy and MS with Jan Janisch-Hanzlik

Jan Janisch-Hanzlik lives with MS and is a participant in one of the clinical trials evaluating the safety and efficacy of CAR-T cell therapy for MS. Jan is the first person in the world to receive this one-and-done treatment, and this week, she's joining me to share her experience participating in the clinical trial. But you'll be especially interested in hearing how CAR-T cell therapy has impacted Jan's MS.

Open enrollment for people with Medicare and for those who get their health insurance through the ACA healthcare.gov Marketplace begins this week, and we're talking about some of the reasons you want to pay particular attention to your 2026 health insurance options.

As the U.S. federal government shutdown enters its third week, we're reviewing some of the ways that the shutdown may affect someone living with MS.

And we're giving you a reminder about how you can add your voice and share your story of living with MS with the FDA by participating in the Shaping Tomorrow Together initiative.

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: A first-hand account of an important clinical trial, open enrollment begins, and how the government shutdown may affect people with MS :22

Open enrollment for Medicare and Marketplace enrolees begins :22

How the federal government shutdown could affect people living with MS 4:29

Your opportunity to tell the FDA what it's like to live with MS 8:57

Jan Janisch-Hanzlik shares her experience participating in a CAR-T cell therapy clinical trial, and how the treatment has impacted her MS 11:28

Share this episode 31:38

Next week's episode 31:57

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Email: jon@realtalkms.com
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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

PARTICIPATE: Take the Shaping Tomorrow Together Survey
https://s.alchemer.com/s3/Perspectives-on-MS

REGISTER: Attend the virtual Shaping Tomorrow Together meeting with the FDA
https://nmss.quorum.us/event/25463

SIGN UP: Become an MS Activist
https://nationalmssociety.org/advocacy

JOIN: The RealTalk MS Facebook Group
https://facebook.com/groups/realtalkms

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https://itunes.apple.com/us/app/realtalk-ms/id1436917200

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REVIEW: Give RealTalk MS a rating and review
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RealTalk MS Episode 424
Guest: Jan Janisch-Hanzlik

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