Ep 190 Starvation: More than hunger

Ep 190 Starvation: More than hunger

Deprived of food, our bodies do the best they can to keep us alive and functioning as long as possible. As the days pass, the rhythms of our lives change: our metabolism, our heartbeats, our hormones, even our thoughts shift to adjust to this period of scarcity. This response is evolutionarily engrained, following a variable but fairly prescribed path. In this episode, we trace that path, exploring what happens when our bodies are not given the energy stores they need, how patterns of metabolism alter, leading our bodies to consume themselves, and the profound consequences this has on every part of our physiology and psychology. We also tell the story of how we came to learn about these outcomes, chiefly through a WWII-era study called the Minnesota Starvation Experiment. This is the first of two episodes centered around malnutrition, starvation, and famine. Next week, we’ll explore the broad topic of famine, of which starvation is merely one component.

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Episoder(282)

Ep 187 Hypothermia Part 2: How it helps

Ep 187 Hypothermia Part 2: How it helps

Last week, we took you through all the ways that cold can harm us and the harrowing history of humans perishing at its icy hands. Ending the story there would be skipping over the parts where cold get...

9 Sep 20251h 5min

Ep 186 Hypothermia Part 1: How it hurts

Ep 186 Hypothermia Part 1: How it hurts

For all our wondrous adaptations as a species - our big brains, our capacity for language, our opposable thumbs - we humans are not well-equipped to deal with the cold. Take us out of our insulated dw...

2 Sep 202557min

Special Episode: Lina Zeldovich & The Living Medicine

Special Episode: Lina Zeldovich & The Living Medicine

The development of antibiotics was one of the greatest turning points in the history of medicine. Bacterial infections that were once death sentences were cured within a matter of days after administr...

26 Aug 202551min

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Ep 185 The Great Smog of London: “Thick, drab, yellow, disgusting”

Some things just go together: peanut butter and jelly, bacon and eggs, milk and cereal, London and smog. Or at least, that’s the way things used to be until the Great Smog of 1952. (Don’t worry, the f...

19 Aug 20251h 14min

Ep 184 The Gallbladder: Humor us

Ep 184 The Gallbladder: Humor us

For most of us, there probably hasn’t been a good reason for you to think about your gallbladder. Ever. Much of the time, it sits there, silently storing, concentrating, and, when needed, churning out...

12 Aug 20251h 22min

Special Episode: Carl Zimmer & Airborne

Special Episode: Carl Zimmer & Airborne

In the first years of the COVID pandemic, a debate raged: was the virus transmitted via respiratory droplets, or was it airborne? For some, this distinction seemed overly technical, pedantic even. But...

5 Aug 202549min

Ep 183 SSRIs Part 2: Action

Ep 183 SSRIs Part 2: Action

Last week, we took you on a journey of discovery and innovation, and this week we’re gonna tell you how the heck it all works. That means a deep dive into the nitty gritty of SSRIs, from what serotoni...

29 Jul 20251h 10min

Ep 182 SSRIs Part 1: Origin

Ep 182 SSRIs Part 1: Origin

Since first hitting the shelves nearly 40 years ago, SSRIs have become one of the most commonly prescribed classes of antidepressants around the world, as well as one of the most discussed and misunde...

22 Jul 20251h 2min

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