TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1346)

TWiV 510: Retroviruses at Cold Spring Harbor

TWiV 510: Retroviruses at Cold Spring Harbor

Vincent and Dickson travel to the 44th Retrovirus meeting at Cold Spring Harbor Laboratories, where they speak with John Coffin, Stephen Hughes, Ya-Chi Ho, and Matt Takata about the meeting and their ...

9 Sep 20181h 4min

TWiV 509: 41,103 bases under the sea

TWiV 509: 41,103 bases under the sea

The TWiV team considers whether those who can do, can't teach, and newly discovered viruses of planarians and Aplysia with the largest RNA genomes. Hosts: Vincent Racaniello, Dickson Despommier, Alan ...

2 Sep 20181h 46min

TWiV 508: Bioweapon

TWiV 508: Bioweapon

Jens returns to present a brief history of bioweapons, with a focus on the program in the Soviet Union, the largest ever undertaken, and his experience working in the decommissioned Soviet bioweapons ...

26 Aug 20182h 7min

TWiV 507: The fusion of form and function

TWiV 507: The fusion of form and function

The TWiV team discuss the biology of Ebola viruses, and how localization of the membrane proteins of vaccinia virus drive function: the fusion machinery sits at the tips of virions, and binding protei...

19 Aug 20181h 58min

TWiV Special: David Tuller is PACEman

TWiV Special: David Tuller is PACEman

David Tuller returns to provide an update of his investigative work to expose the methodological and ethical problems with the PACE trial for ME/CFS. Host: Vincent Racaniello Guest: David Tuller Becom...

17 Aug 20181h 8min

TWiV 506: A Cafeteria full of jelly rolls

TWiV 506: A Cafeteria full of jelly rolls

The TWiVniks explain how the three-dimensional structure of the giant Cafeteria roenbergensis virus suggests a new mode of assembly, and the apparent elimination of dengue fever in an Australian city ...

12 Aug 20181h 37min

TWiV 505: Rosebola

TWiV 505: Rosebola

The TWiV hosts review persistence of Ebola virus after the end of the Liberian outbreak, and the potential role of two herpesviruses in the pathogenesis of Alzheimer's disease. Hosts: Vincent Racaniel...

5 Aug 20182h 2min

TWiV 504: Flying foxes and barking pigs

TWiV 504: Flying foxes and barking pigs

The TWiVerinos discuss Nipah virus and the recent outbreak in India, and the first cast of polio in Papua New Guinea in 18 years. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit,...

29 Jul 20181h 50min

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