TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1346)

TWiV 479: Trypsin the flight fantastic

TWiV 479: Trypsin the flight fantastic

The TWiVome explores induction of antiviral responses by repeating patterns of capsids, and a fungus in the mosquito gut that aids dengue virus replication. Hosts: Vincent Racaniello, Dickson Despommi...

4 Feb 20181h 50min

TWiV 478: A pox on your horse

TWiV 478: A pox on your horse

The TWiV team explains how infectious horsepox virus - likely the ancestor of smallpox vaccines - was recovered from chemically synthesized DNA fragments. Hosts: Vincent Racaniello, Dickson Despommier...

28 Jan 20181h 41min

TWiV 477: Raiders of the lost Arc

TWiV 477: Raiders of the lost Arc

The TWiVodrome explains how a gag-like protein from a retrotransposon forms virus-like particles that carry mRNA  within vesicles across the synapse. Hosts: Vincent Racaniello, Dickson Despommier, Ala...

20 Jan 20181h 43min

TWiV 476: In ACOD1 we trust

TWiV 476: In ACOD1 we trust

Nels joins the TWiV team to talk about his work on genomic accordions in vaccinia virus, hepatitis B virus in a 439 year old mummy, and viral induction of energy synthesis by a long noncoding RNA. Hos...

14 Jan 20181h 44min

TWiV 475: Everything is viral

TWiV 475: Everything is viral

In the first episode for 2018, the TWiV team reviews the amazing virology stories of 2017. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Become a patron of TWiV! Links f...

7 Jan 20181h 50min

TWiV 474: Call me fish meal

TWiV 474: Call me fish meal

The TWiVanguardians take on Bodo saltans virus, a leviathan which infects an abundant flagellated eukaryote in Earth's waters. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spind...

31 Des 20171h 43min

TWiV 473: Assessing a risk and infecting you twice

TWiV 473: Assessing a risk and infecting you twice

The Fellowship of the Virus discuss enhancement of dengue disease in humans: the contribution of antibody concentration and increased binding to Fc receptors. Hosts: Vincent Racaniello, Dickson Despom...

24 Des 20171h 49min

TWiV Special: Ray Ortega in the podcaster's studio

TWiV Special: Ray Ortega in the podcaster's studio

Vincent speaks with professional podcast producer Ray Ortega about his career and the power of the podcast. Host: Vincent Racaniello Guest: Ray Ortega Become a patron of TWiV! Links for this episode ...

20 Des 20171h

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