TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1345)

TWiV 333: Naturally curious chimeras

TWiV 333: Naturally curious chimeras

Host: Vincent Racaniello Guests: Ben Fensterheim, Megan Freeman, Bobak Parang, and Meredith Rogers Vincent returns to Vanderbilt University and meets up with Ben, Megan, Bobak, and Meredith to learn a...

19 Apr 20151h 33min

TWiV 332: Vanderbilt virology

TWiV 332: Vanderbilt virology

Host: Vincent Racaniello Guests: Seth Bordenstein, James Crowe, and Mark Denison Vincent visits Vanderbilt University and meets up with Seth, Jim, and Mark to talk about their work on a virus of Wolba...

12 Apr 20151h 37min

TWiV 331: Why is this outbreak different from all other outbreaks?

TWiV 331: Why is this outbreak different from all other outbreaks?

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiV team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological...

5 Apr 20152h 16min

TWiV 330: A swinging gate

TWiV 330: A swinging gate

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVers explain how a protein platform assists the hepatitis C virus RNA polymerase to begin the task of m...

29 Mar 20151h 50min

TWiV 329: Pox in the balance

TWiV 329: Pox in the balance

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiV team reviews identification of immune biomarkers in CFS/ME patients, and how a cell nuclease controls...

22 Mar 20151h 50min

TWiV 328: Lariat tricks in 3D

TWiV 328: Lariat tricks in 3D

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery a...

15 Mar 20151h 32min

TWiV 327: Does a gorilla shift in the woods?

TWiV 327: Does a gorilla shift in the woods?

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The eTWiVicators review evidence that the HIV-1 group O epidemic began with a single cross-species transmissio...

8 Mar 20151h 42min

TWiV 326: Giving HIV a flat tyr

TWiV 326: Giving HIV a flat tyr

Hosts: Vincent Racaniello, Alan Dove, and Rich Condit The sternutating TWiVers discuss preventing infection of cells and animals by a soluble CD4-CCR5 molecule that binds to HIV-1 virus particles. Lin...

1 Mar 20151h 33min

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