TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1344)

TWiV 284: By the pricking of my thumbs, something wicked this way comes

TWiV 284: By the pricking of my thumbs, something wicked this way comes

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler The TWiV team discusses how skin scarification promotes a nonspecific immune response, and whether remaining stocks of sm...

11 Mai 20141h 42min

TWiV 283: No Reston for the weary

TWiV 283: No Reston for the weary

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Guest: Jens H. Kuhn Jens speaks with the TWiV team about filoviruses, including the recent Ebola virus outbreak in Guinea. Links f...

4 Mai 20141h 50min

TWiV 282: Tamiflu and tenure too

TWiV 282: Tamiflu and tenure too

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiV team reviews a meta-analysis of clinical trial reports on using Tamiflu for influenza, and suggestions on how to rescue U...

27 Apr 20141h 44min

TWiV 281: The Salk legacy with Peter L. Salk

TWiV 281: The Salk legacy with Peter L. Salk

Host: Vincent Racaniello Guest: Peter L. Salk Vincent meets up with Peter L. Salk to talk about development of the first poliovaccine, eradication of poliomyelitis, and Jonas Salk's 100th birth annive...

21 Apr 20141h 30min

TWiV 280: Post viral

TWiV 280: Post viral

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVmeisters answer listener email about the NEIDL, negative results, patenting MERS-coronavirus, human pa...

13 Apr 20141h 38min

TWiV 279: The missing LNC

TWiV 279: The missing LNC

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy reveal how a retrovirus in the human genome keeps embryonic stem cells in a pluripotent state, from where they can dif...

6 Apr 20141h 29min

TWiV 278: Flushing HIV down the zinc

TWiV 278: Flushing HIV down the zinc

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Vincent, Dickson, Alan, and Kathy discuss disruption of the ccr5 gene in lymphocytes of patients infected with HIV-1. Links...

30 Mar 20141h 42min

TWiV 277: My podcast Vinny

TWiV 277: My podcast Vinny

Hosts: Glenn Rall, Ann Skalka, and Vincent Racaniello Glenn and Ann meet up with Vincent to talk about his career in science and science communication. Video of this episode - view at YouTube Send you...

23 Mar 20141h 18min

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