TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1344)

TWiV #127 - Viruses are no joke

TWiV #127 - Viruses are no joke

Vincent, Alan, and Rich explore a novel bunyavirus isolated in China, the recent polio outbreak in Republic of the Congo, and cell to cell transmission of a retrovirus by biofilm-like extracellular as...

3 Apr 20111h 25min

TWiV #126 - Wart's up, doc?

TWiV #126 - Wart's up, doc?

Virologist Michelle Ozbun and the TWiV team review the biology of human papillomaviruses.

27 Mar 20111h 35min

TWiV #125 - TWiV infects FiB

TWiV #125 - TWiV infects FiB

This Week in Virology and Futures in Biotech join together in a science mashup to talk about a virophage at the origin of DNA transposons, and unintended spread of a recombinant retrovirus.

20 Mar 20111h 21min

TWiV #124 - Viruses that make you better

TWiV #124 - Viruses that make you better

Vincent, Dickson, Alan, Rich, and Grant discuss a tanapoxvirus protein that inhibits tumor necrosis factor, purging tumors with myxoma virus, and destruction of the last known stocks of smallpox virus...

13 Mar 20110s

TWiV #123 - Contaminated prostates, absolute truth, and bleached worms

TWiV #123 - Contaminated prostates, absolute truth, and bleached worms

Vincent, Alan, and Rich talk about XMRV integration sites in prostate tumor DNA, the decline effect and scientific method, and the first virus of Caenorhabditis nematodes.

6 Mar 20111h 33min

TWiV #122 - More fun than a monkey full of viruses

TWiV #122 - More fun than a monkey full of viruses

The complete TWiV crew teams up with Welkin Johnson to explore the other AIDS epidemic, infection of monkeys with simian immunodeficiency virus, and its restriction by the cellular protein TRIM5.

27 Feb 20111h 47min

TWiV #121 - Huskies go viral

TWiV #121 - Huskies go viral

A conversation about careers in virology, systems biology, innate immunity, and antiviral research recorded at the University of Washington in Seattle.

20 Feb 20111h 30min

TWiV 120: Ed Niles, a Km Vmax kind of guy

TWiV 120: Ed Niles, a Km Vmax kind of guy

Hosts: Vincent Racaniello, Rich Condit, and Ed Niles Vincent, Rich, and Ed discuss the transition from academic scientist to government work, the general program of drug and vaccine development in the...

13 Feb 20111h 47min

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