TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1343)

TWiV #54 - Professor Lynn Enquist, virology luminary

TWiV #54 - Professor Lynn Enquist, virology luminary

Vincent speaks with Lynn Enquist about his career in virology, moving from academia to industry and back. Along the way he did pioneering research on bacteriophage, participated in the birth of reco...

18 Okt 20091h 27min

TWiV #53 - The ends justify the means

TWiV #53 - The ends justify the means

Vincent, Dick, and Alan talk about Nobel prizes for telomere research, bacteriophages that protect aphids from wasps, salicylates and pandemic influenza mortality, and hand washing. Links for this e...

11 Okt 20091h 1min

TWiV #52 - Scott Hammer, MD on AIDS vaccines

TWiV #52 - Scott Hammer, MD on AIDS vaccines

Vincent and Dr. Scott Hammer talk about different types of AIDS vaccines and how they are tested in clinical trials. Links for this episode: PAVE 100 trial cancelled HIV vaccine shows promise for the...

4 Okt 20091h 10min

TWiV #51 - ALVAC-HIV and AIDSVAX BE

TWiV #51 - ALVAC-HIV and AIDSVAX BE

Vincent, Dick, and Alan (with a cameo appearance by Rich Condit) review the world’s largest Phase III study of a complex HIV vaccine candidate in Thailand, immunization of salmon against infectious ...

27 Sep 20091h 23min

TWiV #50 - XMRV

TWiV #50 - XMRV

Vincent and Jason review influenza 2009 H1N1 vaccine trials and protection against the virus conferred by the 1976 swine flu vaccine, then move on to a virus called XMRV and its possible role in pro...

20 Sep 20091h 14min

TWiV #49 - Viral genomes

TWiV #49 - Viral genomes

Vincent and Dick continue Virology 101 with a discussion of the seven different types of viral genomes, and how to use the pathway to mRNA to understand viral replication. Links for this episode: D...

13 Sep 20091h 2min

TWiV #48 - Outbreaks near you

TWiV #48 - Outbreaks near you

Vincent, Dick, Alan and Rich revisit a vaccinia virus lab accident and viral vaccines produced in plants, then talk about an iPhone app to track infectious diseases, flying foxes, and an inhaled mea...

6 Sep 20091h 19min

TWiV #47 - Vertical vaccine farm

TWiV #47 - Vertical vaccine farm

Vincent and Dick discuss influenza virus-like particle vaccines produced in insect and plant cells, rapid sharing of influenza research, and answer listener questions about cytomegalovirus, viral ev...

30 Aug 20091h 10min

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