TWiV #85 - Hepatitis C virus with Professor Michael Gale

TWiV #85 - Hepatitis C virus with Professor Michael Gale

On episode #85 of the podcast This Week in Virology, Vincent and Michael Gale discuss the origin, pathogenesis, prevention, of hepatitis C virus, and how it evades innate immune responses.

Host links Vincent Racaniello and Michael Gale

Links for this episode:
  • The Gale Laboratory at the University of Washington
  • Incredible view from the Gale laboratory (jpg)
  • Evasion and disruption of innate immune signalling by hepatitis C and West Nile viruses (review)
  • New potent HCV inhibitor
  • HCV virion and genome structures at ViralZone

Episoder(1346)

TWiV 549: The church of protocadherin

TWiV 549: The church of protocadherin

Kartik and Rohit join the TWiV team to present their identification of protocadherin-1 as a cell receptor for New World hantaviruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spin...

26 Mai 20191h 43min

TWiV 548: Mice, shrews, and caterpillars

TWiV 548: Mice, shrews, and caterpillars

Vincent travels to the European Congress of Virology in Rotterdam and with local co-host Marion Koopmans speak with Martin Beer, Stephan Gunther, and Vera Ross about their careers and their work on La...

19 Mai 20191h 11min

TWiV 547: Upstate virology

TWiV 547: Upstate virology

Vincent travels to the University at Albany to speak with Cara, Rachel, and Alex about their careers and their work on stress granules, epitranscriptomics, and arboviruses. Host: Vincent Racaniello Gu...

12 Mai 20191h 35min

TWiV 546: Delta blues and chitlins

TWiV 546: Delta blues and chitlins

The un-encapsidated TWiV Humans discuss finding hepatitis D virus-related sequences in birds and snakes, and fatal swine acute diarrhoea syndrome caused by a coronavirus of bat origin. Hosts: Vincent ...

5 Mai 20192h 2min

TWiV 545: Biocrimes and misdemeanors

TWiV 545: Biocrimes and misdemeanors

Jens Kuhn returns to TWiV to explain Select Agents, Priority Pathogens, Australia List Pathogens, Risk Group Agents, biosafety, biosecurity, and biosurety. Hosts: Vincent Racaniello, Dickson Despommie...

28 Apr 20191h 44min

TWiV 544: Immunogaga

TWiV 544: Immunogaga

The TWiV team reveals the repertoire of anti-viral antibodies in newborn humans, and a complement protein that binds the adenovirus capsid and prevents release of the viral DNA. Hosts: Vincent Racanie...

21 Apr 20191h 47min

TWiV 543: Stoned and senile

TWiV 543: Stoned and senile

The TWiV team discusses Medusavirus, isolated from a hot spring in Japan, and induction of neurodegeneration by recurrent herpes simplex virus 1 infection of mice. Hosts: Vincent Racaniello, Dickson D...

14 Apr 20191h 48min

TWiV 542: Inside Microbiotix

TWiV 542: Inside Microbiotix

Vincent travels to Microbiotix, Inc, a biopharmaceutical company in Worcester, MA to speak with four members of the company about their discovery and development of small molecule drugs that target se...

7 Apr 20191h 5min

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