Lead: Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine

Lead: Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine

Rapid vs Standard Induction to Injectable Extended-Release Buprenorphine

JAMA Network

This industry-sponsored, multicenter, open-label randomized clinical trial with 729 participants, assessed if rapid induction (RI) for initiating extended-release buprenorphine is as safe and effective as standard induction (SI) in individuals who inject opioids or use fentanyl. RI was well tolerated and had higher retention than SI at extended-release buprenorphine injection 2 overall and in fentanyl positive participants. Administering the second extended-release buprenorphine injection 1 week after the first was well tolerated in both the RI arm and SI arm. These findings suggest support RI for extended-release buprenorphine induction in high-risk patients and demonstrate the feasibility of administering the first 2 doses at least 1 week apart.

Read this issue of the ASAM Weekly

Subscribe to the ASAM Weekly

Visit ASAM

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(100)

Lead: Adolescent cannabis use disorder following recreational cannabis legalization in California, USA: A population-based interrupted time series study

Lead: Adolescent cannabis use disorder following recreational cannabis legalization in California, USA: A population-based interrupted time series study

Adolescent cannabis use disorder following recreational cannabis legalization in California, USA: A population-based interrupted time series study Addiction Adolescent past-year cannabis use trends ha...

29 Sep 7min

Lead: Abandonment of prescribed buprenorphine for opioid use disorder, 2020-2024

Lead: Abandonment of prescribed buprenorphine for opioid use disorder, 2020-2024

Abandonment of prescribed buprenorphine for opioid use disorder, 2020-2024 JAMA Network Open This retrospective cohort study examined characteristics associated with abandonment of newly prescribed bu...

22 Sep 8min

Lead: US drug overdose deaths involving stimulants without opioids continued to rise in 2024

Lead: US drug overdose deaths involving stimulants without opioids continued to rise in 2024

US drug overdose deaths involving stimulants without opioids continued to rise in 2024 Addictive Behaviors Reports Drug overdose deaths (DOD) peaked in 2022 before a decline in rates driven by decreas...

15 Sep 7min

Lead: US drug overdose deaths that occurred in isolation, 2022–2024

Lead: US drug overdose deaths that occurred in isolation, 2022–2024

US drug overdose deaths that occurred in isolation, 2022–2024 NEJM Evidence Data were obtained from SUDORS (State Unintentional Drug Overdose Reporting System) for 2022-2024. Of 191,577 overdose death...

9 Sep 7min

Lead: Nicotine e-cigarettes for cigarette smoking cessation: Recommendations to US-based clinicians

Lead: Nicotine e-cigarettes for cigarette smoking cessation: Recommendations to US-based clinicians

Nicotine e-cigarettes for cigarette smoking cessation: Recommendations to US-based clinicians Journal of the American Medical Association This Special Communication summarizes the evidence on the use ...

3 Sep 7min

Lead: Oral semaglutide for alcohol use disorder: A randomized clinical trial

Lead: Oral semaglutide for alcohol use disorder: A randomized clinical trial

Oral Semaglutide for Alcohol Use Disorder: A Randomized Clinical Trial The American Journal of Psychiatry Accumulating preclinical and observational evidence suggests that glucagon-like peptide-1 rece...

25 Aug 7min

Lead: Reflections on the preparation, implementation, and sustainability of a virtual SUD clinic: A public health response to the opioid epidemic

Lead: Reflections on the preparation, implementation, and sustainability of a virtual SUD clinic: A public health response to the opioid epidemic

Reflections on the preparation, implementation, and sustainability of a virtual SUD clinic: A public health response to the opioid epidemic Journal of Substance Use and Addiction Treatment This is an ...

18 Aug 7min

Lead: Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis Addiction

Lead: Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis Addiction

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis Addiction Cocaine use disorder (CUD) is an increasingly wi...

11 Aug 7min

Populært innen Politikk og nyheter

giver-og-gjengen-vg
aftenpodden
forklart
aftenpodden-usa
popradet
fotballpodden-2
stopp-verden
dine-penger-pengeradet
det-store-bildet
rss-espen-lee-usensurert
rss-gukild-johaug
saken
nokon-ma-ga
hanna-de-heldige
aftenbla-bla
rss-ness
rss-penger-polser-og-politikk
e24-podden
bt-dokumentar-2
frokostshowet-pa-p5