BBC Inside Science

BBC Inside Science

A weekly programme that illuminates the mysteries and challenges the controversies behind the science that's changing our world.

Episoder(615)

Window to solve pandemic origins closing

Window to solve pandemic origins closing

Virologist Marion Koopmans is one of the independent researchers appointed by the World Health Organisation to investigate the origins of the coronavirus pandemic. The team visited China in January this year as a first step to answer how, when and where SARS-Cov-2 first infected humans. Professor Koopmans tells Victoria Gill that time is beginning to run out to launch the next phase of studies, to trace the first people in China to be exposed and identify the animals from which the virus jumped the species barrier. Also in the programme:Is the practise of feeding the birds in our gardens creating losers as well as winners, and causing the numbers of some woodland birds to decline? Conservation biologist Alexander Lees visits Victoria in her garden to discuss the question, and reveal the truly dark side of the Great Tit.A new study of the impact of street lighting on nocturnal insects shows that the local impacts on moths can be dramatic. According to entomologist Douglas Boyes, street lights deter female moths from laying their eggs and make them more vulnerable to predation by bats. He's found that artificially illuminated areas are home to half the number of moth caterpillars compared to dark areas.

26 Aug 202128min

Mammoth Journey

Mammoth Journey

A 17,000 year old tusk contains a remarkable story of the lifetime travels of a woolly mammoth which roamed the grasslands of Ice Age Alaska. The animal travelled 70,000 kilometres over the course of three decades before his premature death north of the Arctic Circle. The University of Alaska's Matthew Wooller tells Victoria Gill how his team pieced together the mammoth's life from isotopic clues captured in the tusk.Also in the programme: The search for storage capacity underground for all the hydrogen we'll need for a net zero carbon economy, with geoscientists Katriona Edlmann and Eike Thaysen of the University of Edinburgh.How the 1987 Montreal Protocol (which phased out CFCs) saved us from an even worse climate crisis than the one we're facing, with climate scientist Paul Young of the University of Lancester.Probiotics may protect corals from death by bleaching, with marine biologist Raquel Peixoto of King Abdullah University in Saudi Arabia.

19 Aug 202130min

IPCC report - extreme weather events

IPCC report - extreme weather events

Victoria Gill talks to climate scientist Friedericke Otto about the Intergovernmental Panel on Climate Change's new landmark report. The report this week states that the evidence for humanity's role in changing global change is now unequivocal. Dr Otto was a lead author on the chapter on extreme weather events and explains how human influence can be attributed to the increasing incidence and intensity of heat waves and heavy rainfall events.Also in the programme: Immunological evidence to support a covid vaccine booster programme in the UK, with virologist Jonathan Ball of the University of Nottingham.Faecal transplants that rejuvenated the memory and the brains of elderly mice, with neuroscientist John Cryan of University College Cork. A website for the public to report their sightings and upload their videos of ball lightning, with electrical engineer Karl Stephan of Texas State University, San Marcos.

12 Aug 202130min

Bees and multiple pesticide exposure

Bees and multiple pesticide exposure

Victoria Gill looks at the latest stories from the world of science. In this week's episode: the threat to bees from multiple pesticide exposure, how bee colonies can evolve defences against the varroa parasite, more problems for the Starliner space capsule, and what may be the oldest fossil animals yet found.

5 Aug 202131min

Covid 19 – reaching the unvaccinated

Covid 19 – reaching the unvaccinated

In the UK we have seen a recent fall in Covid 19 cases. Good news, but we don’t know yet if this will be sustained. The virus is now thought to be spreading predominantly amongst the under 30s, most of whom remain unvaccinated. Young adults are the demographic most likely to be vaccine hesitant or vaccine averse. Kavita Vedhara from Nottingham University discusses the delicate balancing act of managing personal choice and collective responsibility needed to persuade people to get vaccinated to help stop the spread of the virus.Forget lab rats, how about lab cats? Leslie Lyons from the University of Missouri says we’ve long neglected the genetic similarities between cats and humans. And that understanding how the diseases we share in common affect our feline friends will help with treatments for ourselves.If you take lots of medicines wouldn’t it be great to have them all in one pill? That’s the aim of Ricky Wildman’s project at Nottingham University – a personalised pill that can be 3D printed to order,And we look at the life of Nobel prize winning physicist Steven Weinberg, famed for his beautifully simple explanations of complex science and also his love of a good argument.

29 Jul 202130min

A life-changing database

A life-changing database

Proteomes, the sequences of protein within the DNA of every living thing, are notoriously difficult to model. The usual chemical methods can take months, but a new computational model using the ability of artificial intelligence to learn the complex sequences is able to predict structures within a matter of hours. Thousands of protein structure predictions are now available on a public database for anyone to access. Understanding such proteins is seen as key to treating nearly all disease. It also hold the potential for improvements in fields as diverse as increasing crop resilience to climate change and biodegrading plastic on an industrial scale. Marnie Chesterton speaks with Demis Hassabis from Deepmind which developed the protein structure prediction system, and Janet Thornton from the European Bioinformatics Institute which holds the database.Genetic engineering, the promise and perils, is the subject of a new series with Matthew Cobb on Radio 4, called Genetic Dreams, Genetic Nightmares. He tells us about the dilemmas now faced by researchers who on the one hand have the potential to send terminator genes into malaria spreading mosquitoes – but who are also aware of the huge unknowns surrounding the release of such technology.Extreme weather events are becoming more frequent. Hayley Fowler has been researching the links between weather systems, climate change and the heat and floods we are currently experiencing.And could we reduce the incidence of SARS-Cov2 with a different vaccination strategy? Julia Gog has modelled different scenarios, as the number of infections continues to rise. A strategy to target those who are mixing the most, whether socially or through their employment, may be more effective than one targeting the most vulnerable.

22 Jul 202132min

Covid19 - should we test everybody ?

Covid19 - should we test everybody ?

Epidemiologist Julian Peto is advocating mass testing as the key part of a plan to stop the virus spreading. Studies where everyone has been tested have picked up asymptomatic cases. With the addition of isolation and contact tracing this method of testing has been able to massively reduce the spread of the virus. The hope is such a coordinated scheme implemented nationally could help bring the numbers down.There’s a question over which type of test is best to use for mass testing. At the moment many of us do lateral flow tests at home. Although they give instant results their accuracy has been shown to be strongly linked to how well the tests are conducted - hence the need to back up any positive findings with the more accurate PCR test. PCR takes longer and needs sophisticated lab equipment. However a compromise could be to use RT Lamp tests, they are accurate, give results in around 20 minutes, do require a very basic lab, but without the expensive equipment of PCR. A number of RT lamp tests have now been developed for SARS-Cov2. Kevin Fong has been to see the developers of one of them, the OxLAMP test. And with the lifting of restrictions how are you going to judge your own personal risk from Covid? It’s a question that interests philosopher of science Eleanor Knox. She says government mandates on mask wearing and social distancing have allowed us to avoid tricky questions around our own potential risk from the virus and risks our own behaviour might pose to loved ones. Now there’s a lot more to think about in terms of balancing our desires to return to some semblance of normality while levels of Covid infection continue to rise. One area that’s come into sharp focus over lockdown is exercise. Some people have been unable to exercise due to Covid restrictions while others have discovered a whole new interest in moving more. A new book ‘Move’ by Caroline Williams explores the links between brain function, evolution and movement. She says staying active is a fundamental part of what makes us human.

15 Jul 202128min

Covid and our ancient ancestors

Covid and our ancient ancestors

A global project looking at the genomes of over 2 million people has found a number of distinct genetic markers which seem to either make Covid infection more likely or the symptoms more severe. Some of these markers are known to be associated with susceptibility to cancer and lung disease. However the researchers say on their own these genetic factors are not determinants of how sick people will become. Underlying health, age and sex and a range of environmental and social factors are likely more important says Andrea Ganna from Finland’s Institute of Molecular Medicine who crunched the numbers.The Royal Society Summer Exhibition has just opened. And this year its an opportunity for more people to get involved than ever before – the event is taking place online. There are a number of workshops and interactive games. We speak to a couple of the participants. Caroline Orr from Teesside University talks about research using supercomputers to make microbes produce a range of biofuels that could replace petrol and diesel, and Tony Peyton from Manchester University tells us how the electromagnetic properties of materials are bring harnessed to improve mine clearance in former war zones. And we go to another exhibition, the Royal College of Art graduate show, and ask the age old question - is it art ? Students Kukbong Kim and Bahareh Saboktakin show us their work with recycled concrete and 3d printing - which looks more like science to us.

8 Jul 202128min

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