What’s Actually Driving Your Testosterone Down? | Signal Ep 3
Most cases of low testosterone in modern men are not a problem with the testes. The number is downstream of body composition, sleep, and energy availability. The wellness-clinic algorithm walks past e...
12 Mai 59min
Progressive Loading Part 3: Why the Novice / Intermediate / Advanced Framework Doesn't Work, and What to Do Instead
Three weeks of stalled squats. The conventional answer is to switch programs because you've crossed into intermediate territory. The data says something else. In Part 3 of the Progressive Loading seri...
5 Mai 1h 51min
Is Your Testosterone Actually Low? Why Higher Testosterone Doesn't Do What You Think | Signal Ep 2
Out of 32 symptoms commonly attributed to low testosterone, only 3 actually correlate with it. All three are sexual. The other 29 — fatigue, brain fog, low mood, weight you can't lose, feeling not qui...
28 Apr 1h 1min
Direct Line April 2026: Stopping Ozempic and Lifting With Osteopenia
Stop a GLP-1 and about two thirds of the weight loss comes back within a year. Three randomized withdrawal trials (SURMOUNT-4, STEP 1 extension, STEP 4) and a new BMJ 2026 systematic review of 37 RCTs...
21 Apr 38min
Is the Testosterone Crisis Real? The Numbers Behind the Headlines | Signal Ep 1
A quarter of men start testosterone without a single lab test. Most boosters don't work. And the "testosterone crisis" headline is half testing artifact, half waistline. Two physicians walk through wh...
14 Apr 40min
Medical Mystery: The Man Who Got Weaker When He Started Training
A 43-year-old man starts exercising and ends up in the ER with a CK over 100x the upper limit of normal. His doctor says it’s from training. We don’t think so. In this episode, Dr. Jordan Feigenbaum a...
7 Apr 1h 15min
Overtraining Syndrome: Causes, Diagnosis, and What's Actually Going On
In 2022, researchers conducted the most rigorous systematic review ever performed on overtraining syndrome — looking specifically for controlled studies that documented a human transitioning from a he...
31 Mar 1h 36min
Episode #391: VO2 Max vs. Cardiorespiratory Fitness, GLP-1 Costs, and the 10,000-Step Myth | Direct Line March 2026 (Free)
In this free preview of the March 2026 Direct Line AMA. Drs. Feigenbaum and Baraki cover: VO2 max versus cardiorespiratory fitness for longevity (are Peter Attia’s targets evidence-based? — with Goodh...
24 Mar 30min
