
Machine learning meets malware, with Caleb Fenton
Patrick McKenzie (patio11) discusses software reversing and AI's transformative impact on cybersecurity with Caleb Fenton, co-founder of Delphos Labs. They explore how LLMs are revolutionizing the tra...
5 Jun 20251h 21min

How to negotiate your salary package
In this episode, Patrick McKenzie (patio11) revisits his widely-shared negotiation essay, which he notes may be the most impactful thing he's done in his career aside from VaccinateCA. The essay cover...
29 Mai 202545min

The capitalist's guide to podcasting, with Ross Rheingans-Yoo
In this episode, Patrick McKenzie (patio11) and returning guest Ross Rheingans-Yoo discuss the strategic advantages of starting a podcast, particularly for professionals seeking to build trust, expand...
22 Mai 20251h 3min

Killing viruses with light, with Jacob Swett
In this episode, Patrick McKenzie (patio11) is joined by Jacob Swett of Blueprint Biosecurity to discuss far UVC technology - a specialized wavelength of UV light that kills airborne pathogens while r...
15 Mai 20251h 1min

Life insurance and your money, with Zac Townsend
In this episode, Patrick McKenzie (patio11) is joined by Zac Townsend, a serial founder and CEO of Meanwhile, a fully regulated life insurance company operating in Bitcoin. They explore the difference...
8 Mai 20251h 20min

Fixing government technology, with Mikey Dickerson
In this episode, Patrick McKenzie (@patio11) is joined by Mikey Dickerson to discuss the complex realities behind government software projects. Mikey shares insights from leading the healthcare.gov re...
1 Mai 202553min

Understanding and wielding power in local government, with Daniel Golliher
In this episode, Patrick McKenzie (@patio11) is joined by Daniel Golliher, founder of Maximum New York, to discuss the opaque mechanics of political power and how everyday people can effectively engag...
24 Apr 202559min

The AI energy bottleneck, with Tim Fist
In this episode, Patrick McKenzie (@patio11) is joined by Tim Fist, Director of Emerging Technologies at the Institute for Progress, to discuss how energy constraints could bottleneck AI development. ...
17 Apr 20251h 6min



















