From First Principles

Hosted by Lester Nare and Krishna Choudhary, this two-story, 2.5-hour special sets the table for Nobel Prize Week with deep dives into two recent Nobel-winning domains—gene editing (CRISPR) and gravit...

2 Okt 20252h 36min

Lester Nare and Krishna Choudhary return for Episode 9 of From First Principles, breaking down the latest breakthroughs across AI, physics, biology, and astronomy. From China’s stunning AI leap with D...

23 Sep 20251h 41min

NASA just dropped what they’re calling the strongest evidence yet for biosignatures on Mars, so we spun up an emergency pod. We break down what the rover actually found in Jezero Crater, why geochemic...

16 Sep 20251h 19min

Hosted by Lester Nare and Krishna Choudhary, Episode 7 of From First Principles covers four stories at the frontier of science and technology. This week, we dive into new telescope data on the interst...

9 Sep 20251h 23min

Hosted by Lester Nare and Krishna Choudhary, Episode 6 of From First Principles covers four groundbreaking stories in science—from rare cosmic explosions to synthetic biology breakthroughs that could ...

2 Sep 20251h 28min

This week we break down four big stories—no PhD required.Reading “inner speech”: Invasive brain–computer interfaces record neurons in motor cortex and decode attempted vs. inner speech into words. Res...

26 Aug 20252h 9min

Interstellar visitor #3 is here. We unpack 3I ATLAS (why it’s moving so fast, why we finally saw a tail, and how Hubble/JWST—and maybe even Juno—could nail down its makeup). Then we dive into the Vera...

19 Aug 20251h 22min

We go from the universe’s first chemistry to tomorrow’s designer biology, swing by Mars to tune Europa Clipper’s ice radar, and finish with a fresh take on the double-slit experiment.In this episodeTh...

14 Aug 20251h 16min