GasGasGas - RemiFentanil and the Minto TCI Model
Remifentanil is an anaesthetist’s dream: ultra-short acting, reliably titratable, and deeply potent. This episode takes a dual-pronged approach, covering both the FRCA-relevant pharmacology of remifen...
9 Jun 202529min
Neuraxial Opioid Kinetics: Spinal & Epidural Analgesia for Regional Anaesthesia
In this explainer episode of GasGasGas, we make our descent into the joyful complexities of neuraxial opiate pharmacology. Why do we bother putting opiates into this space at all? What governs their j...
2 Jun 202523min
Diamorphine (Golden Brown): Opioid Pharmacology for Anaesthetic Practice
In this episode of Gas, Gas, Gas, we drill a figurative oil well into the pharmacology of diamorphine — also known by its more notorious street name, Heroin/Smack/Golden Brown. Diamorphine is a synthe...
30 Mai 202512min
Oxycodone: Synthetic Opioid Analgesic for Perioperative Pain
We are plunging into the pharmacology of oxycodone, a potent semi-synthetic opioid analgesic widely used in perioperative and chronic pain settings. We explore oxycodone's mechanism of action, pharmac...
23 Mai 202515min
Methadone: Long-Acting Opioid for Chronic Pain in Anaesthesia
In this episode of the GasGasGas Primary FRCA podcast, we explore methadone, its pharmacology (pharmacodynamics and pharmacokinetics), diverse receptor activity, and its clinical uses. While tradition...
15 Mai 202512min
Tramadol: Atypical Opioid Analgesic Pharmacology & Clinical Use
This episode takes a dive into the detailed pharmacology of Tramadol focussing on the content for the FRCA Primary exam. We explore its unique multi-mechanism analgesic action, pharmacokinetics, clin...
9 Mai 202513min
Alfentanil: Short-Acting Synthetic Opioid Pharmacology for the FRCA and your Anaesthetic Practice
In this episode of GasGasGas, we explore Alfentanil, a short-acting μ-opioid receptor agonist pivotal for anaesthetic practice. Discovered in 1976 by Janssen Pharmaceuticals, Alfentanil remains a supe...
1 Mai 202522min
Target-Controlled Infusion (TCI): Pharmacokinetic Models for TIVA Anaesthesia
TIVA Models for Propofol particularly the: Marsh, Schnider, and Eleveld TCI models. Avoid the classic pitfalls of blindly trusting a pump. If you’re prepping for the FRCA or just want to master the ‘w...
24 Apr 202536min
