The Human Upgrade: Biohacking for Longevity & Performance

The Human Upgrade: Biohacking for Longevity & Performance

For more than a decade, Dave Asprey - the Father of Biohacking and creator of Bulletproof Coffee - has redefined what’s possible for the human mind and body. After more than a thousand episodes of Bulletproof Radio, he’s taking it to the next level with The Human Upgrade™ - a masterclass in biohacking, longevity, and performance optimization.

Each episode explores cutting-edge science, advanced technology, and proven biohacks to help you upgrade your energy, focus, metabolism, and resilience. You’ll learn from world-class scientists, doctors, innovators, and thinkers leading breakthroughs in mitochondrial health, peptides, hormones, fasting, sleep, neuroplasticity, and more.

This isn’t just self-improvement - it’s human enhancement backed by data.

Every guest, every idea, every protocol you discover here moves you toward a longer, stronger, smarter life.

Join The Human Upgrade™ with Dave Asprey - and learn how to live longer, think faster, and perform better.

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Episoder(1564)

PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316

PhD at MIT: The Longevity Molecule That Reverses Aging (250 Studies) : 1316

Learn how to slow, and even reverse, your biological age with cutting-edge science on the molecule that controls your longevity. Host Dave Asprey sits down with Dr. Leonard Guarente, an MIT PhD and on...

19 Aug 20251h 8min

Still Fasting in 2025? Here’s How to Make It Work Better : 1315

Still Fasting in 2025? Here’s How to Make It Work Better : 1315

How do you activate your body’s natural repair system? How can you hack stem cells for faster recovery, brain optimization, and peak human performance? This episode reveals how to trigger stem cell re...

15 Aug 202559min

How to Make Life-Changing Decisions Without Fear – Joe Hudson  : 1314

How to Make Life-Changing Decisions Without Fear – Joe Hudson : 1314

How do you make tough decisions? How do you make them without fear or lying? This episode shows you how unresolved emotions disrupt decision-making, relationships, and functioning in peak brain perfor...

14 Aug 202552min

The New Poisons Lurking Around You – Save Your Longevity : 1313

The New Poisons Lurking Around You – Save Your Longevity : 1313

Toxins you cannot see are damaging your health, wrecking your metabolism, and quietly accelerating aging. This episode reveals how to detect the new poisons lurking in your home, how they sabotage mit...

12 Aug 202558min

Jim Kwik: What I Take to Biohack Brain Speed and Focus  : 1312

Jim Kwik: What I Take to Biohack Brain Speed and Focus : 1312

Want to think faster, remember more, and rewire your brain for high performance? This special archived episode breaks down the real nootropic stack, neuroplasticity tools, and brain optimization proto...

8 Aug 202559min

Why I Inject a “Female Hormone” 3x a Week (Nootropic Hacking)  : 1311

Why I Inject a “Female Hormone” 3x a Week (Nootropic Hacking) : 1311

What if the most powerful upgrades for brain energy, metabolism, and drive aren’t in mainstream medicine, but in rare peptides and misunderstood hormones? In this episode, you’ll discover the cutting-...

7 Aug 20251h 38min

Top 5 Dopamine Boosting Biohacks for Superhuman Energy  : 1310

Top 5 Dopamine Boosting Biohacks for Superhuman Energy : 1310

Ready to learn about the secret compounds, molecules, nootropics, and stacks that Big Pharma doesn’t want you to know about? This episode is packed with the exact dopamine-boosting compounds, stacks, ...

5 Aug 20251h 4min

Protein vs. Plants: The 50g-a-Meal Biohacking Rule  : 1309

Protein vs. Plants: The 50g-a-Meal Biohacking Rule : 1309

Getting 50 grams of protein per meal may be the single most underrated biohacking protein strategy for muscle growth, metabolism, and longevity. In this episode, you’ll discover why animal protein vs ...

1 Aug 202547min

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