The Human Upgrade: Biohacking for Longevity & Performance

(ZBiotics sponsored this episode.)IN THIS EPISODE OF THE HUMAN UPGRADE™… you'll find out how to counter the sometimes rough morning after you have alcohol. The key is a new genetically engineered pre-alcohol probiotic drink. Great timing as you head into the holiday season of celebrations.Zack Abbott, CEO & co-founder of ZBiotics, joins this 1,000th episode of the podcast to talk about new discoveries in alcohol metabolism, genetic engineering and GMOs (used in a good way!), and the power of microbes.Ever wondered why you feel like crap the morning after drinking alcohol? The cause is a byproduct called acetaldehyde that forms in your gut when you drink alcohol. The ZBiotics Pre-Alcohol Probiotic Drink breaks down acetaldehyde while you drink so you can feel better the morning after.Prior to starting ZBiotics, Zack, who has a Ph.D. in microbiology and immunology, worked in clinical trial design, researched HIV vaccines, and pursued novel antibiotics in both academia and industry.He invented the ZBiotics proprietary technology using genetic engineering to develop new probiotics—ones with specific, unique abilities to improve your daily life. He’s proving through science that incredible things can be done with GMOs and genetically engineered microbes.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://zbiotics.com/dave and use code "dave" to save 15%.Watch this episode on YouTube! Biostack for High Performance: https://vatellia.com, use code DAVE2022 to save 10% or subscribe and save 15% + receive a free bottle of Kale BusterHarness Cold to Improve Health & Performance: https://www.cryobuilt.comBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultation See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Nov 202255min

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Sperm that swim together increase their chances of fertilizationLate-night eating is worse than you thoughtMetabolic markers can be measured through your sweatEye movements during REM sleep could delete unwanted memoriesEPISODE SPONSOR: Humic & fulvic minerals provide critical cellular support. Go to https://www.beamminerals.com and use code DAVE20 to get 20% off. Learn more: How Minerals Combat Glyphosate’s Harm – Caroline Alan – #948.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

25 Nov 20228min

Timeline Nutrition sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… immunologist Anurag Singh, M.D., Ph.D., MBA, Chief Medical Officer at Amazentis, joins the show to talk about urolithin A’s connection between inflammation, aging and your mitochondria. Urolithin A activates mitophagy and renews your mitochondria. “It takes all the cellular garbage that has been accumulating over the aging process,” Dr. Singh explains. “It revs it up, so it recharges. And so now, you're cleaning your metabolic waste products much more efficiently and they become the building blocks. This is mitochondrial biogenesis, and that means newer, healthy mitochondria coming in.”This new conversation takes an exciting turn into immunity and your immune system’s two lines of defense: innate and adaptive. You’ll learn:how inflammation plus aging (AKA inflammaging) contributes to a weakened immune system and a growing incidence of cancer as you age;how inflammaging and cancer are connected to mitochondrial dysfunction specifically during the aging process; andhow to approach your immune health differently with this new knowledge.A new study recently published in Immunity looks at how immune cells fight cancer better with a focus on immune modulation, immune cell exhaustion and immune responses. “A lot of urolithin A is anti-inflammatory, but a lot of it is immune modulation," Dr. Singh says. "So, it takes a rewiring of the immune system and makes it more conducive to stopping harmful immune responses.”Watch this episode on YouTube!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: To learn more about the benefits of urolithin A, go to https://www.timelinenutrition.com and use code UPGRADE10 to get 10% off the plan of your choice. WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Go Deep on Relaxation & Sleep: https://balooliving.com/dave, use code DAVE for a special discount. Must-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount. Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Nov 202250min

IN THIS EPISODE OF THE HUMAN UPGRADE™… Robynne Chutkan, M.D., joins the show to talk about a topic that’s foundational to biohacking—resilience. More specifically, resilience that starts in the gut. You’ll learn:how your microbiome continually evolves and why that matters to the state of your gut and body functions.how to strengthen the antiviral defenses located in your gut.why your body’s own ability “to resist, heal, and recover from viruses is vastly superior” to pharmaceuticals.what to do before taking antibiotics to protect your gut, as well as what you can do to rehab your microbiome after antibiotic use.“Being on the winning team when battling viruses isn’t because of good luck, or coincidence, or variations in viral virulence,” Dr. Chutkan explains in her newest book, “The Anti-Viral Gut: Tackling Pathogens from the Inside Out.” "It’s due to differences in us, the hosts, and our defenses, and those differences are what determine your outcome. Put another way: it’s less about the potency of the pathogen and more about the health of the host.”Dr. Chutkan is a Yale- and Columbia-educated integrative gastroenterologist who’s been advancing knowledge and education about gut health for decades. Nearly 20 years ago she founded the Digestive Center for Wellness to help people get to the root issue of their digestive issues and improve their gut health. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Brain Training with Sound & Vibration: Change unwanted behaviors, reduce negative self-talk, and enhance motivation and performance. Go to www.braintap.com/dave to get 30% offMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discount.Get Fit in Five Minutes: https://www.carolbike.com, use code HumanUpgrade to get 2 years of free membership (a total savings of $360) on the CAROL Bike 2.0 and a 100-day home trial.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Nov 20221h 17min

Eight Sleep sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… you’ll learn about the intimate relationship between performance and sleep and how you can hack both with a combination of tech and lifestyle. Matteo Franceschetti joins the show to talk about high performance—something he experienced in athletics, business and life. He was a competitive athlete in his native Italy and a race car driver across Europe. He started two clean-tech companies on two continents. He also worked at the top tier of the international legal worldThe one thing he didn’t excel at was sleep. So, he co-founded Eight Sleep nearly a decade ago to hack sleep in all the ways that fuel human potential, performance and energy.Eight Sleep mattress and mattress pad technology redesign sleep with AI and machine learning models to track your nighttime biosignals. It’s a technology that’s catching the attention of professional athletes in sports like snowboarding, CrossFit, Formula One, and many more.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://www.eightsleep.com/dave/ to get up to $450 off a Sleep Fit Holiday Bundle that includes the Pod 3 Cover. This is a limited-time offer. Eight Sleep currently ships within the USA, Canada, the UK, Australia and select countries in the EU.Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Mattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesShield Yourself from EMFs: https://quantumupgrade.io, use code DAVE to get a two-week free trialSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

15 Nov 202249min

BiOptimizers sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™… you're going to get into bed with the topic of sleep. Pretty much everyone’s favorite. In this conversation, veteran biohacker and BiOptimers co-founder Matt Gallant returns to the show with some straight talk about how to get more and better sleep. He’s spent the big bucks—about $50K he estimates—exploring, experimenting and upgrading his own sleep. He's sharing what he now knows so you can create a sleep stack that supercharges your own energy.You’ll learn about the most common sleep disruptors and what to do about them. You’ll also learn to recognize sleep stages and how to improve your sleep pathways.This fun show uncovers the practical sleep devices, wearables, supplements and lifestyle hacks that will lull you to sleep. So many times, you’re tired and you know you want to go to sleep—and yet—your body and mind just don’t connect. The new Sleep Breakthrough makes that connection for you. And when cortisol runs amok and falsely perks you up with a second wind, you’ll know what to do. More and better sleep means you’ll be a higher-performing human. So, get some tonight!SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://sleepbreakthrough.com/dave and use code DAVE10 to get an extra 10% off. Watch this episode on YouTube!WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Sleep Better on Natural Memory Foam: https://myessentia.com/daveasprey, use code DAVE to get an extra $100 off an Essentia mattress purchase on top of Essentia’s Black Friday 25% off sale plus get two FREE organic pillows ($330 value) with mattress purchase. Through Nov. 27, 2022, only. Cooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep SystemMust-Have Magnesium: https://magbreakthrough.com/dave, use code DAVE10 to get a 10% discountSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Nov 20221h 8min

Alitura Naturals sponsored this podcast.IN THIS EPISODE OF THE HUMAN UPGRADE™…… you’ll learn about skincare ingredients that can either nourish or harm your skin. You’ll find out about standards in skin care products, what “clean beauty” means, and what to look for on product labels.Andy Hnilo, founder of Alitura Naturals, joins the show to talk about skin fitness from the inside out and why using skincare products with ingredients found in nature is the way to go. That means things like pearls, meteorites, clay, CoQ10, enzymes and more.This conversation gets into ways you can get better skin by:choosing the right nutrient-rich specialty products you can apply topically; pairing natural skin products with other biohacks, like red light;making nutrition and fitness upgrades; andexploring supplements, peptides and other wellness options.Improving skin health also means avoiding fillers and chemicals. Toxins both in skin care products and the environment tremendously impact your skin. Acne no longer drives only teenage angst. Adult acne continues to rise, with women affected more than men. Acne affects more than 50% of women between the ages of 20 and 29 and more than 25% of women between the ages of 40 and 49. (American Academy of Dermatology 2012.) Andy himself struggled with acne—so he knows the toll it takes from outside appearance to inner emotional roil. So, he searched for answers: “It was the products that I was using and then also what I was ingesting,” Andy says. “What I was putting into and onto my body.”This get-smart guide to product ingredients, environmental awareness and lifestyle tips can help you find your own skin solutions. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://alitura.com and use code humanupgrade to save 20% sitewide.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT! Upgrade Your Air Quality: https://hypoair.com/Dave/Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideKickstart Autophagy: https://timelinenutrition.com/DAVE, use code ASPREY10 to get 10% off any planSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Nov 202249min

Analemma sponsored this episode.IN THIS EPISODE OF THE HUMAN UPGRADE™… you’re listening to a new Upgrade Spotlight series. Once a month, these shorter episodes feature guests who get right into useful information in a Q&A style. You’ll find out how to improve your energy and upgrade your performance. You’ll also get the latest knowledge about powerful tools and technologies that allow you to change your biology and the environment around you. Introducing Analemma! During this Upgrade Spotlight with Mario Brainovic, CEO of Analemma, you’re going to find out about a tool that transforms regular water into a supercharged, full-spectrum, coherent state. The kind of water you drink absolutely influences the quality of your life. You’ll learn the science behind Analemma and what it can do for your health and energy.Why water? You think you know the basics: stay hydrated daily, avoid plastic bottles and use a filtration system at home. Well, Analemma says water goes way beyond the basics—all the way down to your cellular level. You’re 70% water in body mass, but 99% water on a molecular level. You’re basically very clever water. The Analemma device—similar in looks and function to a magic wand—radically changes the state of drinking water. Environmental forces cause H2O molecules in drinking water to behave chaotically. At an atomic level, water molecules crash into each other constantly. Your body’s susceptible to that influence.“We found a way to bring order to this chaos,” Mario says. “When you swirl an Analemma through the water, what happens is that those same H2O molecules start forming a liquid crystalline structure. They start behaving harmonically. They, colloquially speaking, join hands.”Analemma water is not exclusion zone water. It's something different. “It also is structured water, but we came to it in a very different way,” Mario says. “The key element to it is its stability.”This conversation gets right into the science of Analemma and several studies. You’ll find out how:a new study is measuring the rise in ATP levels (in mitochondrial energy) when people drink this water.this water affects the human microbiome this water reduces your biological age by one to 12 years by regenerating your cellular system, according to GlycanAge.you get an instant balancing effect between the left and the right brain hemispherehow a cooling affect happens on your brainwaves almost instantly when drinking this waterthis water restores the biodiversity of infertile soilSPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: Go to https://analemma-water.com and use code dave10 to save 10%.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Nov 202242min