The secrets of alzheimer's disease

The secrets of alzheimer's disease

Anything about Alzheimer's disease: pathology, biology, medicine, etc.

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Episoder(18)

Brain on Fire: Unpacking the Inflammatory Cascade in Neurodegenerative Disease

Brain on Fire: Unpacking the Inflammatory Cascade in Neurodegenerative Disease

Neuroinflammation represents a pivotal pathological mechanism intricately linked to the onset and progression of a spectrum of neurodegenerative disorders, including Alzheimer's disease (AD), Parkinso...

22 Mai 202517min

Beyond Plaques and Tangles: The Surprising Role of Myelin Makers in Alzheimer's

Beyond Plaques and Tangles: The Surprising Role of Myelin Makers in Alzheimer's

Despite the remarkable progress in elucidating the roles of microglia and astrocytes in AD, the exploration of oligodendrocytes, another major glial cell type, in the context of this neurodegenerative...

22 Mai 202527min

RNA's Sticky Notes: How Tiny Modifications Could Be Key to Unraveling Alzheimer's Disease

RNA's Sticky Notes: How Tiny Modifications Could Be Key to Unraveling Alzheimer's Disease

The potential roles of a new type modification on RNA in AD context.

22 Mai 20258min

Decoding Brain Inflammation: How One Tiny Protein Holds a Powerful Key

Decoding Brain Inflammation: How One Tiny Protein Holds a Powerful Key

An m6A reader moderates the neuroinflammatory response through translation regulation.

3 Mai 20257min

The Brain's Unsung Heroes: How Star-Shaped Cells Hold New Keys to Fighting Alzheimer's disease

The Brain's Unsung Heroes: How Star-Shaped Cells Hold New Keys to Fighting Alzheimer's disease

Alzheimer's disease (AD) stands as a prevalent and debilitating neurodegenerative disorder, primarily affecting the aging population. It is characterized by a progressive decline in cognitive function...

2 Mai 20257min

Brain Clean-Up Crew Gone Rogue: The Double-Edged Sword of Microglia in Alzheimer's

Brain Clean-Up Crew Gone Rogue: The Double-Edged Sword of Microglia in Alzheimer's

Recent research has further illuminated the concept of "stressed" microglia and their altered functions in driving neurodegeneration. Activation of a cellular stress pathway known as the integrated st...

1 Mai 20257min

Fire in the Brain: Alzheimer's Hidden Driver - Neuroinflammation

Fire in the Brain: Alzheimer's Hidden Driver - Neuroinflammation

Alzheimer's disease (AD) represents a significant and growing global health challenge, characterized by progressive cognitive decline and neurodegeneration. While the accumulation of amyloid-beta (Aβ)...

30 Apr 20257min

Tangled Up: Unraveling the Mystery of Tau in Brain Disease

Tangled Up: Unraveling the Mystery of Tau in Brain Disease

Neurodegenerative diseases represent a growing global health crisis, characterized by the progressive dysfunction and loss of neurons in the central nervous system.1 Among the pathological hallmarks o...

29 Apr 20259min

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