The Sepsis Spectrum

The Sepsis Spectrum

Forget everything you ever read in a textbook when it comes to antimicrobial resistance (AMR) and sepsis complications – because they rarely play by the rules. They evolve, adapt, and strike before it’s too late. While classic symptoms like fever, tachycardia, and hypotension are well known, the real challenge lies in recognizing the unexpected to reduce your mental list of those unknown, unknowns. Hosted by Critical Care RN & CNS Author Nicole Kupchik, The Sepsis Spectrum is an exploration of real-world patient cases, expert insights, and clinical deep dives to unravel the most complex presentations facing modern medicine. Through gripping stories and in-depth interviews, Nicole examines diagnostic challenges, cutting-edge treatments, and the growing threat of AMR. Designed for healthcare professionals at every level, The Sepsis Spectrum is about leaving you with more than compelling stories—it’s a vital resource in podcast form. Whether you’re at the bedside or in the classroom, you’ll finish each episode with practical, life-saving knowledge—and earn free CE Contact Hours for Nurses along the way. The fight against sepsis and AMR starts with recognition — because the most dangerous threats are the ones you don’t see coming. A Sepsis Alliance Podcast CME Available: Sepsis Alliance is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Nursing CE Contact Hours Available: Sepsis Alliance is a provider approved by the California Board of Registered Nursing, Provider Number CEP17068. Most U.S. states accept CE provided through the California Board of Registered Nursing, but nurses in other states should check with their local and state accrediting bodies to confirm. Canadian and non-US based nurses should consult their provincial or territorial regulator to confirm acceptance. Other healthcare professionals will receive a certificate of attendance.

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Episoder(17)

When Sepsis Hits the Lungs

When Sepsis Hits the Lungs

Sepsis doesn’t just overwhelm the body, it can turn the lungs into ground zero for multi-organ dysfunction. In this episode, host Nicole Kupchik sits down with Dr. Julie Bastarache to explore how seps...

23 Des 202547min

What happens to the kidneys during sepsis?

What happens to the kidneys during sepsis?

Acute kidney injury (AKI) is far more dangerous and complex than previously understood. In this episode, host Nicole Kupchik sits down with Dr. Gonzalo Matzumura to break down what really happens insi...

16 Des 202546min

 Is the gut the real engine of sepsis?

Is the gut the real engine of sepsis?

Host Nicole Kupchik is joined by Dr. Kaveh Hoda to unpack one of the most overlooked drivers of sepsis: the gut. Often called “the motor of MODS,” the GI tract can push the body toward recovery, or ac...

9 Des 202541min

 Can sepsis turn the liver against you?

Can sepsis turn the liver against you?

In this episode, Nicole Kupchik sits down with Dr. Craig Jenne to unravel how the liver’s immune response shifts during sepsis. Together, they explore how an organ known for detoxifying and defending ...

2 Des 202536min

The Nerve That Could Stop Sepsis

The Nerve That Could Stop Sepsis

What if the key to controlling inflammation, and even saving lives from sepsis, lies not in the bloodstream, but in the brain? In this episode, Nicole Kupchik talks with Dr. Kevin J. Tracey, President...

25 Nov 202541min

Can sepsis break your heart?

Can sepsis break your heart?

When sepsis strikes, the damage doesn’t always end with the infection. Nicole Kupchik is joined by Dr. Mitchell Elkind from the American Heart Association to explore how inflammation during sepsis can...

18 Nov 202538min

What's next in sepsis? | Season 2 Coming Soon!

What's next in sepsis? | Season 2 Coming Soon!

Season 2 is just around the corner for The Sepsis Spectrum! In this special bonus episode, Nicole Kupchik reflects on what we learned last season, how cancer can’t keep her away, and what’s next for t...

29 Sep 202523min

Are we failing sepsis survivors who need us most?

Are we failing sepsis survivors who need us most?

What you don’t track, you can’t fix, and too often, we’re not even looking. Nicole is joined by sepsis survivors Dr. Hilary Spangler and Jackie Duda, along with pediatric ICU nurse-scientist Dr. Mallo...

19 Aug 202539min

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