Iatrogenic Cerebral Amyloid Angiopathy (CAA) and CAA related inflammation (CAA-ri)
The papers summarized focus on Cerebral Amyloid Angiopathy (CAA), particularly the emerging clinical phenomenon of iatrogenic CAA (iCAA). iCAA is hypothesized to occur following the transmission of Am...
15 Okt 202525min
Early Tirofiban After Thrombolysis for Ischemic Stroke (ASSET-IT trial)
This original article published in the New England Journal of Medicine reports the findings of the ASSET-IT trial, a phase 3, multicenter, double-blind, randomized, placebo-controlled clinical trial...
6 Okt 202522min
Friedreich’s ataxia - A Comprehensive Look
Friedreich’s ataxia is a rare, progressive, autosomal recessive neurodegenerative, multisystem disorder caused by a homozygous GAA repeat expansion in the frataxin gene, resulting in a deficiency of t...
5 Okt 202530min
CADASIL Unmasked
This episode combines three papers to provide a comprehensive overview of Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL), emphasizing its status a...
5 Okt 202536min
TTR Familial Amyloidosis Genotype-Phenotype Correlation
The two research articles reviewed here compare the clinical presentation of different variants of hereditary transthyretin-mediated amyloidosis (TTR familial amyloidosis), particularly focusing on th...
28 Sep 202515min
Spinal Bulbar Muscular Atrophy: Canadian Best Practice Recommendations
This episode reviews clinical practice guideline developed for the management of Spinal Bulbar Muscular Atrophy (SBMA), also known as Kennedy disease, in Canada. The guideline is prompted by the disco...
24 Sep 202513min
2025 Revised Criteria for Vascular Cognitive Impairment
This episode reviews the VasCog-2-WSO Criteria, which is the 2025 revised consensus diagnostic guidelines for Vascular Cognitive Impairment and Dementia (VCID). Developed by an international consortiu...
21 Sep 202513min
Idiopathic Normal Pressure Hydrocephalus: Incidence, Progression, Diagnosis and Treatment
This episode reviews 5 publications on Idiopathic Normal Pressure Hydrocephalus (iNPH), specifically addressing diagnosis, patient selection for shunting, and long-term treatment outcomes. One article...
21 Sep 202530min
