
CRISPR babies scandal – more details
Extracts from unpublished papers on the methods used by a Chinese scientist to genetically modify the embryos of two girls reveal a series of potentially dangerous problems with the procedure and ethical shortcomings.We look at the mechanism behind the formation of our facial features and how this is linked to our evolution, scrutinise the impact of current emissions on global climates and see why lithium, used in batteries and medicines, is now a potentially widespread pollutant.66 million years ago, a huge asteroid hit the earth, wiping out most of the dinosaurs that roamed the land. It would still be tens of millions of years before the first humans appeared - but what if those dinosaurs hadn’t died out? Would we ever have evolved?CrowdScience listener Sunil was struck by this thought as he passed a Jurassic fossil site: if dinosaurs were still around, would I be here now? We dive back into the past to see how our distant mammal ancestors managed to live alongside huge, fierce dinosaurs; and why the disappearance of those dinosaurs was great news for mammals. They invaded the spaces left behind, biodiversity flourished, and that led – eventually – to humans evolving. It looks like our existence depends on that big dinosaur extinction.But we explore a big ‘what if?’: if the asteroid hadn’t hit, could our primate ancestors still have found a niche – somewhere, somehow - to evolve into humans? Or would evolution have taken a radically different path: would dinosaurs have developed human levels of intelligence? Is highly intelligent life inevitable, if you give it long enough to develop? We look to modern day birds - descendants of certain small dinosaurs who survived the asteroid strike - to glean some clues.(Photo: He Jiankui, Chinese scientist and professor at Southern University of Science and Technology in Shenzhen. Credit:Reuters)
8 Des 20191h 11min

New Malaria target
Molecular scale investigations have identified the mechanism which confers resistance to antimalarial drugs. Researchers hope work to turn off this mechanism could mean cheaper well known antimalarials can become effective once again. We look at the threat to weather forecasting from 5G networks, discuss the origins of much of the technology in our mobile phones and ask what food we’ll be eating in the future and how the past can inform this.Science fiction is full of people settling on distant planets. But even the closest stars would take millennia to reach with current speeds of travel, by the time any passengers reached an extra solar planet, they would be long dead.So CrowdScience listener Balaji asked us to find out whether humans could hibernate for interstellar travel?To uncover the science fact behind this idea, Anand Jagatia holds a tiny hibernating dormouse at the Wildwood Trust in Kent, and meets Dr Samuel Tisherman who puts his patients into suspended animation for a couple of hours, to save their lives after traumatic injuries that cause cardiac arrest. We ask if Dr Tisherman’s research could be extended to put healthy individuals to sleep for much longer periods of time?It’s a question that neuroscientist, Professor Kelly Drew is studying, in Alaska Fairbanks. She uses Ground Squirrels as a model to understand internal thermostats, and how hibernating mammals manage to reduce their core temperatures to -3 degrees Celsius.Anand speculates wildly with science fiction authors Adrian Tchaikovsky and Temi Oh whose characters in their books ‘Children of Time’ and ‘Do You Dream of Terra Two?’ traverse enormous distances between habitable planets.But is human stasis something that would actually be useful? John Bradford is the director of SpaceWorks, this company works with NASA to try to investigate human hibernation for space travel. He’s trying to make space-based human hibernation a reality, and it seems that may be closer than you’d think.Image: Mosquito. Science Photo Library
2 Des 201956min

Politics and Amazonia’s fires
This year’s Amazon fires have been worse than since 2010, scientists blame a government attitude which they say has encouraged deforestation. Government funded scientists have contributed anonymously to the finding – fearing for their jobs.Food crops and fungus are not normally seen as compatible, but a mutually beneficial relationship between these organisms may help reduce the need for chemical fertilisers and combat climate change.Hayabusa 2, the Japanese space mission is returning to earth after its mission to blast a crater in a distant asteroid.And how the chemistry of protein analysis is helping psychiatrists and emergency medics deal with the effects of the street drug spice.(Image: A Brazilian Institute for the Environment and Renewable Natural Resources (IBAMA) fire brigade member is seen as he attempts to control hot points during a fire. Credit: Reuters/Bruno Kelly)
24 Nov 20191h 4min

Australia burning
Australia’s annual wild fires have started early this year, drought is a factor but to what extent is ‘Bush fire weather’ influenced by climate change?A two million year old fossil tooth reveals some biological answers to who its owner was.Why Climate change may have killed off the world’s first superpower And a hologram produced from sound waves.Can machines read our minds? We go in search of the latest efforts to connect brains to computers. We learn how researchers are combining brain scans with machine learning to generate large amounts of information. We explore how this technology might be used to help people with serious medical conditions like locked-in syndrome. And discover there are many hurdles to overcome along the way – for example how can scientist develop implants that can access the brain without causing long-term damage? Our listener Daniel wants to know whether we might finally be on the cusp of enabling machines to meld with our minds.(Image: Firefighters tackle a bushfire to save a home in Taree, Australia. Credit Peter Parks/AFP via Getty Images)
17 Nov 201956min

Climate in crisis
Pledges to reduce greenhouse gas emissions are largely unachievable says a major audit of commitments to the Paris Climate Accord. Air pollution in Delhi is so bad, breathing the toxic particles has been likened to smoking. Can a scientific assessment of the multiple causes help provide a way forward? We examine a new way of making new plastic – from old plastic. And why sending some stem cells to the international space station might help astronauts travel further. We’re all familiar with the sensation of sleepiness – heavy eye-lid, that warm, fuzzy feeling. But, one listener wants to know, what’s actually going on in our body and brain when tiredness takes over?We investigate how our psycho-motor skills are affected by fatigue in a driving simulator. And we ask how does sleepiness change with age? Why, when tired, do adults crave a nap but children become ever more excitable? And what the hell’s going on with teenagers? We have some answers.(Image: Tourists wearing masks to protect themselves from smog in New Delhi, India. Credit: Sushil Kumar/Hindustan Times via Getty Images)
10 Nov 20191h

Wildfires and winds in California
The Santa Ana in the south, and the Diablo in the north, are winds that are fuelling the terrible fires raging in California this week. They’re also blamed for bringing down power lines that sometimes start the fires. Roland Pease talks to Janice Coen of the National Center for Atmospheric Research NCAR who has been developing a highly detailed model to forecast how wind, mountains, and flames interact during a wildfire. The glaring gaps in human genetics are in Africa – much overlooked because the companies and universities sequencing DNA are mostly based in Europe, the US and other advanced economies. A ten-year attempt to fill in some of those gaps came to fruition this week, with the release of a study covering thousands of individuals from rural Uganda. Deepti Gurdasani, of Queen Mary University London, explains the data reveal both new medical stories, and the scale of past migration within Africa. There are also gaps in the climate record from Africa. Knowing past climates could help massively in understanding the prospects for climate change in coming years on the continent. Journalist Linda Nordling has just published an article in Nature that shows that the records exist – old weather data collected since the 19th Century. It’s just they’re scattered, unexamined, in vaults and collections across Africa. Most of us take the ability to speak fluently for granted but for listener Breeda it has been a lifelong struggle. She has asked us to investigate whether there is a cure for stuttering and if not, what is the best way to live with it is. Breeda is not alone as stammering is a neurological condition that affects 70 million people worldwide. (Image: A firefighter sets a back fire along a hillside during firefighting operations to battle the Kincade Fire in Healdsburg, California. Credit: Philip Pacheco/ /AFP via Getty Images)
3 Nov 20191h 2min

Is quantum supremacy ‘garbage’?
A quantum computer has performed a calculation considered impossible for conventional computers, but how meaningful is the result? As our guest reveals, this quantum state can be hugely significant and garbage – at the same time. Also we look at a new method of gene editing, which avoids cutting up DNA, get to grips with where the worlds worms live and watch elements being created in distant solar collisions.Listeners Michael and Ricky have been walking a tributary of the River Thames in London, UK. They’ve noticed that there are loads of fish, which have only returned in recent years thanks to clean water initiatives. But what about salmon, they wonder? Could they one day return too? If they popped some salmon eggs in the river, would they return to spawn later on in their lives?We head to Norway to find out whether it’s possible. There, we follow the life cycle of salmon, from birth to death and travels to the salmon’s spawning grounds, before following their path out to sea and beyond. We explore the science behind ‘natal homing’ - returning to the place of your birth in order to reproduce. It isn’t just confined to salmon. But how does it work? (Photo: A quantum circuit from Google's Sycamore computer. Credit: Google)
27 Okt 20191h 12min

Malaria, origins and a potential new treatment
A variety of malarial parasites have existed amongst the great apes for millennia, we look at how one of them jumped species and why humans became its preferred host. And from Antarctica we hear about a potential new treatment for malaria found in a deep sea sponge. We also look at why improved monitoring is changing our perceptions of earthquakes and follow the story of an endangered Polynesian snail.What exactly is the relationship between mathematics and reality? That’s the impossibly difficult question we have been set this week by our listener Sergio in Peru. It’s one that’s been pondered by humans for millennia: the Greek philosopher Pythagoras believed “All is number”.Is maths a human construct to help us make sense of reality - a tool, a model, a language? Does maths create its own reality? Or is it reality itself?(Photo: A young gorilla. Credit: Hermes Images/AGF/Universal Images Group via Getty Images)
20 Okt 20191h 1min