Biohacking News Weekly Update : 1383

Biohacking News Weekly Update : 1383

This episode covers:


• FDA Loosening Supplement Warning Labels

The FDA is considering a rule change that would allow supplement companies to include the DSHEA disclaimer only once per package rather than next to every claim. Dave explains why fewer visible warnings could make marketing look more like medical claims, and why biohackers should treat labels as advertising rather than evidence. He shares how to protect yourself now: add one variable at a time, run baseline labs, and rely on data instead of packaging.

Source: https://www.nbcnews.com/health/health-news/fda-supplements-warning-label-rule-change-rfk-jr-rcna249321

• Quantum Sensors for Early Heart Attack Detection

Mayo Clinic is testing a contactless heart-monitoring system called CardiAQ using quantum magnetic sensors and AI noise filtering. The device reads subtle electromagnetic signatures from the heart and compares them to invasive angiography. Dave breaks down why earlier detection of ischemia could shift heart care from reactive treatment to proactive screening — and why building baseline metrics like VO₂max, blood pressure and HRV today will pay off when next-gen diagnostics arrive.

Source: https://www.sandboxaq.com/press/sandboxaq-collaborates-with-mayo-clinic-on-novel-cardiac-diagnostics

• Sauna Detox for Microplastics

Emerging research shows that sweating meaningfully removes plastic-related chemicals like BPA and phthalate metabolites from the body, often more efficiently than blood or urine alone. Sauna use amplifies this effect by increasing circulation, mobilizing stored toxins from tissues, and accelerating sweat-based excretion. When you combine regular heat exposure with reduced environmental plastic contact, you create a powerful detox strategy that targets a chemical burden once thought unavoidable. Dave breaks down how sauna protocols can support toxin elimination, improve cardiovascular resilience, strengthen autonomic balance, and help counteract the metabolic and hormonal disruptions linked to microplastics in modern life.

Source: https://superage.com/can-you-sweat-out-microplastics-in-the-sauna/

• Psychedelics and Longevity Biomarkers

Bryan Johnson treated a guided psilocybin experience as a structured longevity experiment, collecting nearly 250 biomarkers including CGM, stress markers, HRV and Kernel brain imaging. The experiment revealed a surprising metabolic change: mean glucose dropped 8 percent, variability fell 11 percent, and estimated HbA1c moved from 4.7 to 4.4 — similar to months of metformin but after a single session. Dave explores the emerging idea that neuroplastic events might influence glucose regulation through brain-pancreas signaling, while emphasizing the need for supervised, legal use and proper clinical trials.

Source: https://www.businessinsider.com/bryan-johnson-trip-on-mushrooms-five-hours-live-2025-12


• A Mitochondrial Protein that Extends Mouse Lifespan

Researchers boosted the mitochondrial protein COX7RP and extended mouse lifespan by ~6.6 percent while improving insulin sensitivity, lipid handling, endurance and liver fat metabolism. COX7RP supports formation of mitochondrial “supercomplexes,” improving respiratory efficiency and ATP generation. Dave explains how this reinforces lifestyle levers — strength training, aerobic capacity, stabilizing blood sugar — as tools that likely preserve supercomplex architecture and mitochondrial resilience.

Source: https://www.eurekalert.org/news-releases/1109082


All source links provided for direct access to the original research and reporting.


This episode is designed for biohackers, longevity seekers and high-performance listeners who want practical strategies rooted in cutting-edge science. Dave Asprey translates emerging research into actionable upgrades for your biology — from metabolism and mitochondria to nervous system health, detox, and prevention.


New episodes every Tuesday, Thursday, Friday, and Sunday.


Keywords: FDA supplement rule change, supplement warning labels, DSHEA disclaimer removal, supplement regulation risks, quantum cardiac scanner, Mayo Clinic heart attack detection, AI heart monitoring, early ischemia detection technology, sauna detox evidence, sweating out toxins research, BPA phthalate sweat studies, microplastics sauna myth, Bryan Johnson psilocybin experiment, psychedelic longevity research, psychedelic metabolic reset, glucose control psychedelics, HbA1c psilocybin results, continuous glucose monitor insights, mitochondria lifespan research, COX7RP protein aging study, mitochondrial supercomplex benefits, ATP energy output aging, metabolic flexibility longevity, biohacking news update, anti-aging science breakthroughs, evidence-based longevity tools, biological age biomarkers


Thank you to our sponsors!

-BEYOND Conference 2026 | Register now at https://beyondconference.com/

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Resources:

• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

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• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com

Timestamps:

0:00 - Intro

0:18 - Story 1: FDA Supplement Label Changes

1:43 - Story 2: CardiAQ Heart Scanner

2:59 - Story 3: Saunas and Microplastics

4:58 - Story 4: Psychedelics and Blood Sugar

8:22 - Story 5: Mitochondrial Longevity Research

10:29 - Weekly Wrap-Up

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The Science of Supper: Transform Your Health Through Family Meals – Shawn Stevenson : 1142

The Science of Supper: Transform Your Health Through Family Meals – Shawn Stevenson : 1142

Today’s guest is none other than Shawn Stevenson. If you’re not already familiar with Shawn’s work, he’s the author of the USA Today National bestseller Eat Smarter, the international bestselling book Sleep Smarter, and the creator of the widely popular health podcast, The Model Health Show.Shawn is one of those guys who embodies peace and calm, after an impressively transformative journey stemming from a background of health challenges at least as severe as mine. After recovering, he became a researcher and nutritionist experienced in biology and nutritional science. We dive into a crucial element of biohacking I am always keen to highlight—friendship, or in this case, community.Based on research from Shawn’s latest book, Eat Smarter Family Cookbook, we talk about his current mission on the path to wellness: creating a culture of wellness around the dinner table, how communal meals impact our health and longevity, and filling the void of connection we all so desperately need these days. Shawn shares insights from his own family’s dinner table, his tips for implementing family meals into your weekly routine, and the encouraging science and data behind how it supports physical and spiritual nourishment, nervous system regulation, stress management, and more.If you like this episode, I encourage you to go pick out a good cut of meat and cook food for someone you care about—or simply do anything that's an act of service that nourishes another human being. Here’s to cultivating strong relationships, imbuing our food with love, and honoring the act of nourishing ourselves and our families.(00:01:16) Cultivating Peace & Presence Through Nervous System Regulation(00:10:00) Cultural Connections to Health, Longevity & Childhood Obesity(00:25:20) Family Dinners for Nourishment, Mindfulness & Building Stronger Bonds(00:43:45) Kids in the Kitchen: Fostering Enjoyment, Skill & Service in Cooking(00:59:48) Heart Meditations, Trauma Healing & the Science of Emotional ExchangeSponsorsBioptimizers | Go to Bioptimizers.com/Dave for 10% off any order.LeelaQ | Visit LeelaQ.com/Dave for 10% off your order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/booksPodcast: The Model Health ShowInstagram: @shawnmodelYouTube: The Shawn ModelRead: Eat Smarter Family Cookbook by Shawn StevensonThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Mars 20241h 17min

Why Your Own Mind Is Holding You Back – Peter Crone : 1141

Why Your Own Mind Is Holding You Back – Peter Crone : 1141

Today’s guest has the coolest title I’ve ever heard—mind architect. Peter Crone is a world-renowned spiritual teacher, mind-body wellness coach, and life transformation expert. He’s worked with everyone from athletes, to actors, to billionaire CEOs, to everyday people trying to do their best. Peter helps people achieve spiritual freedom, mental peace, and physical vitality, which all align with biohacking in a big way.In this episode, we dig deep into the limiting beliefs that shape our behavior and relationships. We talk about discerning between reality and the stories we tell ourselves. Peter gives advice on overcoming perfectionism, strengthening your intuition, and recognizing your innate value. We also explore how to reframe language, the value of curiosity, and how to harness losses into learnings that unlock your greatest potential. It’s a fascinating conversation. You can hear more from Peter at the upcoming Biohacking Conference. Get your tickets at biohackingconference.com. (00:03:33) Where Biohacking Meets Energy Work(00:06:28) Accessing a Spiritual State Without Drugs(00:11:04) Recovering From Perfectionism(00:19:14) Reality vs. the Stories We Tell Ourselves(00:29:42) Healing Wounds From Birth(00:38:31) Why Fear Is the Enemy of Health(00:43:18) How To Train & Strengthen Intuition(00:56:01) Recognizing Your Innate Value(01:03:30) How Can We Learn From Our Elders?(01:06:19) Peter’s Freedom ProgramSponsorsTimeline Nutrition | Go to TimelineNutrition.com/Dave to get 10% off your first order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: petercrone.comInstagram: @petercroneFacebook: Peter Crone - The Mind Architect TikTok: @petercroneofficial YouTube: @PeterCroneOfficialThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Mars 20241h 16min

No Grain, No Pain: Why Removing Gluten is Key to Improving Your Health – Dr. Peter Osborne : 1140

No Grain, No Pain: Why Removing Gluten is Key to Improving Your Health – Dr. Peter Osborne : 1140

Today, we're diving into a topic that's on everyone's mind, but often misunderstood: gluten. Joining the show on this gluten-decoding mission is none other than Dr. Peter Osborne, aka the Gluten-Free Warrior. Dr. Osborne is a powerhouse of knowledge in nutritional health, particularly regarding gluten sensitivity and food allergies. As the founder of Gluten Free Society, the author of the bestseller, No Grain No Pain, and the host of the Glutenology MasterClass Series, he's at the forefront of functional medicine, helping countless individuals combat chronic and autoimmune diseases. His insights are crucial for anyone navigating the complexities of a gluten-free life.In this episode, we explain why gluten isn’t good for anyone—even if you don’t have symptoms or a diagnosed celiac problem. As a foundation, we lay out the differences between gluten sensitivity and celiac disease, covering the surprising connections between dairy, gluten allergies, and mold. Dr. Osborne also highlights why common gluten-free substitutes like corn, oats, and rice aren't the safe havens we wish we were. You’ll hear about the nefarious ways Big Food is keeping our country sick and how to start taking charge of your own health in simple, free ways.Dr. Osborne shares his recommended diet, the rule of thirds, and how to effectively shift your eating habits. He recognizes the frustration and struggle many people face in finding effective professional help, and shares his tips for spearheading your own healing while collaborating with competent professionals.This episode isn't just about gluten; it's a deep dive into understanding your body, your diet, and how to collaborate with your doctor to find the health solutions that work for you.(00:01:48) Why We Should All Be Gluten Free(00:11:46) Big Food’s Role in Our Declining Health(00:28:31) When to Enjoy (and Avoid) Sugar, Soybeans & High Oxalate Foods(00:42:39) Change Your Diet & Biohack Your Way to Better Health(01:00:15) How To Respectfully Advocate for Your Own HealthSponsorsBEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order.Viome | Go to Viome.com/Dave to save $110 on the Full Body Intelligence Test.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: drpeterosborne.comRead: No Grain, No Pain by Peter OsborneYouTube: Peter OsborneInstagram: @drosborneThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Mars 20241h 20min

Akashic Records 101: The Simple Spiritual Practice You Haven’t Heard of…Yet – Laura Coe : 1139

Akashic Records 101: The Simple Spiritual Practice You Haven’t Heard of…Yet – Laura Coe : 1139

Today we’re talking about something a little different—the “weird,” esoteric, metaphysical stuff. I’m joined by Laura Coe, who was a successful healthcare tech entrepreneur before selling her company and returning to her passion for philosophy. She is now an author, certified life coach, and Akashic Records reader. Never heard of the Akashic Records? Laura explains exactly what they are, and how they can help you understand yourself on a deeper level to find more joy, peace, and prosperity in your life. We explore the big questions… Who can access the Records? How do you know if they’re even real? Then, we get into the nitty gritty… How do you learn to read them? What can you ask and not ask? Can they help you sell your house or make more money? Laura and I also talk about how to tap into your intuition as an entrepreneur, the stigmas against spirituality, and why more of us than we think probably have psychic gifts. If you’re skeptical of this stuff, I’m going to ask you to suspend your disbelief and listen with an open mind. Laura’s perspective will give you a lot to think about. Why not give it a try? (00:03:47) What Are The Akashic Records?(00:13:15) The Akashic Records as a Grid of Interconnection(00:18:47) Validating The Akashic Records for Skeptics(00:23:37) Coming Out As Spiritual(00:26:53) How Long Does It Take To Learn The Akashic Records?(00:29:42) The Craziest Questions People Ask(00:32:39) Listening to Your Inner Knowing(00:38:01) What Can’t You Ask The Akashic Records?(00:41:55) Sentences That Open the Records(00:47:22) Healing Yourself Through Healing Others(00:48:54) Can It Help You Sell Your House?(00:56:11) Taking the “Woo Woo” out of The Akashic RecordsSponsorsMitosynergy | Get 15% off now at Mitosynergy.com/DaveCalroy.com | Head over to Calroy.com/Dave for an exclusive discountResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: lauracoe.comThe Little Soul School: littlesoul.schoolRead The Nature Of Series: lauracoe.com/booksInstagram: @laurascoeThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Feb 20241h 2min

How a Celebrity Trainer Rose to Success – Jason Walsh : 1138

How a Celebrity Trainer Rose to Success – Jason Walsh : 1138

Today I’m talking with one of the most sought-after celebrity trainers on the planet. Jason Walsh has trained stars like Matt Damon, Miles Teller, Brie Larson, and Bradley Cooper for some of the most physically demanding roles of their careers. He’s also the founder of Rise Nation, a global fitness studio powered by the VersaClimber, where you train like an athlete. On today’s episode, we talk about how Jason rose to success as a celebrity trainer. He shares the moments that defined his life and career, plus his advice for anyone who wants to get started in the fitness industry. We also go deep on the painful parts of entrepreneurship—unpacking the betrayals and heartbreaks we’ve both experienced as founders. We explore ways to train your brain and your body for resiliency, and how to redefine forgiveness as an energetic shift. We also talk about Jason’s new protein company, Rise 311. Plus, his take on why you don’t need to train for an hour a day to get results. (00:02:06) How Jason Became a Celebrity Trainer (00:22:22) The Rewards of Being Disciplined (00:25:40) How to Rise in Your Fitness Career(00:33:52) Building Rise Nation Step by Step (00:40:13) The War Against Small Businesses (00:42:47) Heartbreaks & Betrayals in Business (00:48:23) Train Your Brain to Reframe Trauma (00:53:47) Redefining Forgiveness (01:00:33) The Rise of Rise 311(01:02:32) Finding Joy & Resilience SponsorsMitosynergy | Get 15% off now at https://Mitosynergy.com/DaveCalroy | Go to https://Calroy.com/Dave for an exclusive discountResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: rise-nation.comRise 311: rise311.comInstagram: @risenationJason’s Instagram: @risemovementTikTok: @climbrisenationThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Feb 20241h 9min

Beat Sugar: The Glucose Goddess Method – Jessie Inchauspé : 1137

Beat Sugar: The Glucose Goddess Method – Jessie Inchauspé : 1137

Blood sugar management as a biohack captures attention for its innovative approach to health. Today's guest, Jessie Inchauspé, stands out as an expert in guiding practical glucose management, smarter nutritional choices, and unveiling the intricate relationship between diet, blood sugar levels, and overall well-being. Behind the popular Instagram account @GlucoseGoddess, Jessie educates millions on groundbreaking food habits and has achieved notable success as a French biochemist and New York Times bestselling author, with over a million copies sold of her works, "Glucose Revolution" and "The Glucose Goddess Method," in 40 languages.Her unique combination of mathematics and biochemistry expertise opens up the secrets of blood sugar and its significant impact on physical and mental health. The conversation zeroes in on Jessie's mission to make complex science accessible through simple, transformative tips. Topics include her groundbreaking research, The Glucose Method study, the launch of her Anti-Spike supplement, and her signature four hacks for glucose management after consuming carbs. The dialogue also covers the benefits of real versus fake sugar, the underlying causes of insulin resistance and diabetes, and how blood sugar spikes influence aging.This episode unveils Jessie's remarkable discoveries and biohacks for glucose management, which are crucial for fertility, PCOS, and understanding the health impacts of lifestyle choices like alcohol and nicotine. Jessie's practical insights offer a path to enjoying favored foods with minimal bodily impact, appealing to both biohacking aficionados and those embarking on a health journey.(00:02:28) Understanding Glucose’s Role in Our Health(00:14:27) Enjoying Carbs Without Negative Side Effects(00:23:27) The Real Cause of Insulin Resistance & Diabetes(00:34:23) Addressing Alcohol, Nicotine & The French Paradox(00:54:22) The Glucose Goddess Method Study(01:05:47) Glucose Management for Fertility, PCOS & PMS CravingsSponsorsTimeline Nutrition | Go to TimelineNutrition.com/Dave and get 10% off your order.Sunlighten | Head to Sunlighten.com/dave to save up to $600 when you order.ResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: glucosegoddess.comInstagram: @glucosegoddess Read: Glucose Revolution by Jessie InchauspéRead: The Glucose Goddess Method by Jessie InchauspéThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Feb 20241h 16min

Variable Resistance: The Ultimate Muscle Hack – Dr. John Jaquish : 1136

Variable Resistance: The Ultimate Muscle Hack – Dr. John Jaquish : 1136

Today we're talking about testosterone replacement and unpacking the novel concepts of progressive overload and variable resistance training—both methods to gain, and keep, muscle mass in your body without living in the gym.I’m joined by strength expert, entrepreneur, past guest of the show, and PhD, John Jaquish. John has spent years researching and developing improved approaches to health. Inventor of X3, a technology that is proven to develop muscle much faster than conventional weight lifting with the lowest risk of joint injury, Dr. Jaquish’s methods are used in training the world's most elite athletes as well as Olympians.Aligning with the most basic tenet of biohacking, if you can achieve all of your physical or athletic goals in half the time of your competitors, why not explore the option? John is as gracious as he is informed in this one, detailing the benefits of variable resistance training and indulging me in a super deep dive into diet and nutrition experimentation, testosterone replacement therapy, and efficient muscle growth.You’ll learn what he eats every day to look as good as he does. You’ll get repetition-count-specific recommendations on ultra-quick workout routines. And you’ll learn the very surprising amount of carbohydrates I ingest every single day (a number that will shock many of you).SponsorsBEAM Minerals Pets | Go to BeamMinerals.com/DAVE2024 for 20% off your first order.ARMRA | Try it out for yourself at tryarmra.com. Use code DAVE to get 15% off your first order.(00:02:39) Masterclass on Efficient Muscle Building(00:16:43) How are Shaolin Monks & Gymnasts So Strong? (00:23:46) Testosterone Replacement Therapy (TRT)(00:38:40) How Protein Impacts Muscle Growth(00:47:55) Breakthrough Personal Research on Carbohydrates(00:58:31) Weight Lifting is a Waste of TimeResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Website: jaquishbiomedical.comInstagram: @drjaquishYouTube: Jaquish BiomedicalRead: Weight Lifting Is a Waste of TimeRead: Osteogenic Loading: A New Modality To Facilitate Bone Density DevelopmentHow to Build Strength Faster – John Jaquish, Ph.D. #863Building Strength Isn’t About Weight Lifting Anymore – John Jaquish, Ph.D. #862The Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Feb 20241h 6min

Upgrade Spotlight: Glutathione for Ageless Skin : 1135

Upgrade Spotlight: Glutathione for Ageless Skin : 1135

Welcome to a special Upgrade Spotlight Edition, where I introduce you to someone who's genuinely changing the game. Our carefully selected guest today is a renowned pharmacist, an author, and a pioneer in biohacking for skin longevity: Dr. Nayan Patel. Dr. Patel is a trailblazer in the world of antioxidants, specifically glutathione. If you've been following biohacking or are a regular listener, you know that glutathione is a key antioxidant with vital functions, including skin health. Dr. Patel's expertise in absorbable glutathione and anti-aging sciences is unparalleled.Dr. Patel holds a unique patent for transdermal glutathione delivery, a groundbreaking method of introducing this crucial antioxidant directly through your skin with his company Auro Wellness. His book, The Glutathione Revolution, dives deep into this topic. In this episode, we delve into why glutathione is essential for skin longevity. Dr. Patel shares insights on his innovative formula and technology for absorption at Auro Wellness, which has shown promising results in reducing fine lines, cellulite, and even promoting hair growth. As someone who champions scientifically-backed products and real results, I'm excited to discuss how Dr. Patel's work is a true game changer. I know the power of glutathione. I've been using it for nearly two decades, especially during my battle with toxic mold exposure. And now, thanks to innovators like Dr. Patel, we're moving from intravenous methods to transdermal applications—it's truly revolutionary. For those eager to try, visit aurowellness.com and use code DAVE10 for a discount.(00:01:14) Biohacking Benefits of Glutathione & New Absorption Technology(00:08:32) The Auro Skincare Stack & How Glutathione Enhances Skin Longevity(00:20:13) Reducing Cellulite & Fine Lines with Glutathione (00:35:01) Glutathione for Hair Growth & Toxin RemovalResourcesDave Asprey’s NEW Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books Shop Auro Wellness: aurowellness.com (use code DAVE10 for 10% off)Read: The Glutathione Revolution by Dr. Nayan Patel and Dr. Mark HymanThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Feb 202443min

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