Audio long read: Will blockbuster obesity drugs revolutionize addiction treatment?
Nature Podcast29 Dec 2025

Audio long read: Will blockbuster obesity drugs revolutionize addiction treatment?

Anecdotal stories suggesting that weight-loss drugs can help people shake long-standing addictions have been spreading fast in the past few years, through online forums, weight-loss clinics and news headlines. And now, clinical data are starting to back them up.


Over a dozen randomized clinical studies testing whether GLP-1 drugs like Ozempic can suppress addiction are now under way, and neuroscientists are working out how these weight-loss drugs act on brain regions that control craving, reward and motivation.


Scientists warn that the research is still in its early stages, but some researchers and physicians are excited, as no truly new class of addiction medicine has won approval from regulators in decades.


This is an audio version of our Feature: Will blockbuster obesity drugs revolutionize addiction treatment?

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