The Aliquot Preview25 Feb 2021

PREVIEW Aliquot #6: Genetic and lifestyle risk factors for Alzheimer's disease

The single most important genetic risk factor for Alzheimer's disease is a variant of apolipoprotein E, or APOE for short, a lipoprotein produced in the liver and brain. Roughly a quarter of all people living in the US – about 75 million people – carry a genetic variant of APOE called APOE4. Having APOE4 is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease. But having APOE4 doesn't mean that Alzheimer's disease is inevitable. In fact, lifestyle behaviors can modulate risk for the disease, too, especially sleep, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk. Understanding our genetic risks and addressing lifestyle behaviors – especially our sleep patterns – can influence whether a person eventually develops Alzheimer's disease.

These Aliquot segments feature Dr. Dale Bredesen, a professor of neurology, and Dr. Matthew Walker, a professor of neuroscience and psychology.

(00:00) Introduction
(02:37) ApoE4 increases Alzheimer's disease risk, but healthy habits can reduce risk (Dale Bredesen discussion)
(05:20) People who are ApoE4+ have 2x the risk of having sleep apnea (Matthew Walker segments)
(12:03) Glial cells are the sewage system for the brain

You can see the original full interview with Dr. Bredesen You can see the original full interview with Dr. Walker Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more. Learn more and sign up at: www.foundmyfitness.com/crowdsponsor

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Avsnitt(25)

PREVIEW Aliquot #106: The Science of Longevity Vitamins: Taurine, Ergothioneine, and PQQ

Get more Aliquots! Become an FMF Premium Member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, every-other-week Science Digest emails, and more. Learn mor...

30 Apr 202435min

PREVIEW Aliquot #92: The Underestimated Role of Resistance in Body Recomposition

Having a healthy body composition, with plenty of lean mass – in the form of muscle and bones – is essential for health throughout the lifespan. Achieving a healthy body composition requires a balance...

11 Aug 202336min

PREVIEW Aliquot #85: The Science of Wrinkle Prevention ⎯ Building Resilient Skin

Your skin is a crucial barrier to the outside world – the first line of defense against environmental exposures, and the primary means by which the body retains fluids necessary for survival. Conseque...

18 Apr 202325min

PREVIEW Aliquot #78: The minimum effective dose for hypertrophy

Incorporating resistance training into your exercise regimen presents a scheduling dilemma – there's simply not enough time. Performing time-efficient workouts that involve supersets, paired sets, dro...

14 Jan 202320min

PREVIEW Aliquot #70: Preventing age-related muscle loss

The progressive loss of skeletal muscle mass and strength that occurs with aging, referred to as sarcopenia, begins as early as our 30s or 40s. Many factors contribute to sarcopenia, including diet an...

22 Okt 202232min

PREVIEW Aliquot #65: Concerns with chronic NSAID use

Non-steroidal anti-inflammatory drugs, or NSAIDs, are among the most widely used drugs worldwide, available in both prescription and over-the-counter forms, such as aspirin, ibuprofen, naproxen, and o...

31 Aug 202226min

PREVIEW Aliquot #61: How dietary fiber influences metabolic health

Dietary fiber is a broad term that refers to the non-digestible components of fruits and vegetables. Gut microbes break down certain types of fiber, releasing micronutrients trapped in the fiber matri...

19 Juli 202232min

PREVIEW Aliquot #59: How alcohol affects sleep, behavior, and cancer risk

Alcohol, one of the most used drugs worldwide, is a controversial subject. Whereas some research suggests drinking alcohol improves health, an abundance of evidence indicates that drinking alcohol als...

20 Juni 202232min