Why LDL Rises in Perimenopause and What Your Cholesterol Panel Isn't Telling You | Dr. Darshan Shah

Why LDL Rises in Perimenopause and What Your Cholesterol Panel Isn't Telling You | Dr. Darshan Shah

Angela and special guest Dr. Darshan Shah, look at the polarising world of cardiovascular health, specifically demystifying the role of LDL cholesterol. They challenge the traditional one-size-fits-all approach to statins, arguing that heart health must be viewed through the lens of individual biology—where factors like inflammation, genetic risk, and lifestyle can make the same LDL level a non-issue for one person and a crisis for another WHAT YOU WILL LEARN LDL is Not Always the Enemy: A high LDL reading alone doesn’t guarantee heart disease; its impact depends on individual context The Power of ApoB and Lp(a): Traditional cholesterol panels are often insufficient; more modern biomarkers like ApoB(a superior risk marker) and Lp(a) (a genetic factor) provide a much clearer picture of cardiovascular risk. AI in Diagnostics: The Clearly scan uses AI to analyse CT angiograms, allowing doctors to see the actual buildup of both calcified and soft plaque in the coronary arteries rather than just guessing based on blood work. Precision Over Dogma: Because cardiovascular health is an "N-of-1" situation, interventions like statins or PCSK9 inhibitors should be based on actual arterial health TIMESTAMPS: 01:21 The LDL Controversy: An explanation of why cholesterol remains a polarizing topic and why it must be treated as an individual biology issue. 02:37 The Tale of Two Patients: A comparison of a healthy gym-goer with high LDL/zero plaque versus a high-stress professional with lower LDL/significant plaque. 04:13 Modern Biomarkers: A breakdown of the specific tests to ask for, including ApoB, HS-CRP, and the Clearly cardiovascular scan. VALUABLE RESOURCES • Take the BioSyncing Quiz to help you understand what’s actually happening in your body — and how to fix it. 👉 https://biosyncing.scoreapp.com/ ABOUT THE HOST Angela Foster is an award winning Nutritionist, Health & Performance Coach, Speaker and Host of the High Performance Health podcast. A former Corporate lawyer turned industry leader in biohacking and health optimisation for women, Angela has been featured in various media including Huff Post, Runners world, The Health Optimisation Summit, BrainTap, The Women’s Biohacking Conference, Livestrong & Natural Health Magazine. Angela is the creator of BioSyncing®️ a blueprint for ambitious entrepreneurial women to biohack their health so they can 10X how they show up in their business and their family without burning out. CONTACT DETAILS ⁠Instagram⁠ ⁠Facebook⁠ ⁠LinkedIn⁠ Disclaimer: The High Performance Health Podcast is for general information purposes only and do not constitute the practice of professional or coaching advice and no client relationship is formed. The use of information on this podcast, or materials linked from this podcast is at the user's own risk. The content of this podcast is not intended to be a substitute for medical or other professional advice, diagnosis, or treatment. Users should seek the assistance of their medical doctor or other health care professional for before taking any steps to implement any of the items discussed in this podcast. This Podcast has been brought to you by Disruptive Media. ⁠https://disruptivemedia.co.uk/

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I Spent 5 Days at the World’s #1 Longevity Clinic—The Surprise It Revealed about My Health

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Healthy on Paper: The Hidden Drivers of Cancer Risk in Midlife

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13 Juli 1h 4min

The Real Causes of Perimenopause Brain Fog (A Neurologist Explains)

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If you've been told that perimenopause and menopause inevitably lead to permanent cognitive decline and "brain fog," the neuroscience says otherwise. In this episode, neurologist and Neuroscience Aca...

10 Juli 12min

Dr. Eric Helms: Why You Don't Need to Lift Heavy to Build Muscle and Strong Bones After 40

Dr. Eric Helms: Why You Don't Need to Lift Heavy to Build Muscle and Strong Bones After 40

If you've been told that menopause means muscle loss, weight gain, and declining strength are inevitable, the science says otherwise. In this episode, world-renowned strength scientist Dr. Eric Helms...

5 Juli 1h 2min

Why Lifting Weights Alone Isn't Making You Lose Fat in Perimenopause (And What Actually Works)

Why Lifting Weights Alone Isn't Making You Lose Fat in Perimenopause (And What Actually Works)

In this Bitesize episode, we revisit a key conversation on why resistance training and fat loss need to be treated as two separate goals — and why blending them usually backfires. This short-form cut ...

2 Juli 11min

The Natural Ozempic Alternative for Weight Loss | Sarah Kennedy

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Sarah Kennedy of Calocurb explains why food noise spikes in perimenopause: falling estrogen raises cravings while the hindbrain overrides forebrain willpower under stress or poor sleep. She contrasts ...

29 Juni 45min

Dr. Stacy Sims on Zone 2 Confusion, HIIT vs Sprint Training & The Truth About Wearables

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Most of us have heard that we need to exercise more, but today, exercise physiologist Dr Stacy Sims digs into what kind of training actually moves the needle for women — and why longer, slower workout...

25 Juni 14min

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