Season 2 Episode 1 BCL-2 Inhibitors: Driving Cells to Destruction

Cigall Kadoch had a hunch that the research in her lab might be relevant to endometrial cancer research. She had spent more than a decade studying the molecular machinery that unwinds DNA in the nucle...

1 Sep 19min

As our universe of knowledge expands, sometimes incrementally and more often, exponentially, its new dimensions create new challenges. The more we know, the better our tools are, the more choices we h...

17 Maj 202328min

If there is such a thing as a holy grail in cancer research, a secret spell or golden ring that can ward off any and all forms of the disease, it probably lives somewhere in the realm of immunotherapy...

26 Apr 202332min

By the early 2000s, researchers at Dana-Farber and elsewhere knew that a certain protein appeared in many tumors taken from lung cancer patients. Based on that data, doctors started treating those pat...

5 Apr 202330min

Cancer is often a problem of cell division; cancer cells keep doubling and doubling, faster and faster. Eventually, they crowd out the healthy cells we need to survive. So researchers proposed a quest...

15 Mars 202326min

Momentum isn't always one way. And it's not always constant. Sometimes it shoves you sideways, sometimes it stops you in your tracks. And sometimes only sometimes, it drives you to write one of the mo...

22 Feb 202328min

In season 2 of Unraveled, we explore the theme of momentum. The momentum that takes therapies from test bench to bedside, and then back to test bench for fine tuning. The momentum provided by research...

27 Jan 20232min