Can Computer Simulations Provide Trustworthy Regulatory Evidence?

Can Computer Simulations Provide Trustworthy Regulatory Evidence?

This episode asks: Can computer simulations provide credible regulatory evidence?

Learn about the hierarchical framework that ensures the trustworthiness of virtual trials, using a Lego analogy to break down complex processes into manageable pieces. Understand how virtual devices, patients, and even surgeons are modelled to reflect real-world scenarios.

We also discuss the broader implications of this innovative framework and how it could lead to faster, more personalized, and more inclusive medical device development. Tune in to uncover the future of medicine and the role you can play in shaping it.

Aycock KI, Battisti T, Peterson A, Yao J, Kreuzer S, Capelli C, Pant S, Pathmanathan P, Hoganson DM, Levine SM, Craven BA. Toward trustworthy medical device in silico clinical trials: a hierarchical framework for establishing credibility and strategies for overcoming key challenges. Front Med (Lausanne). 2024 Aug 12;11:1433372.

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(43)

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Digital Twins & Virtual Patients: Revolutionising Paediatric Clinical Trials

Join us for an eye-opening exploration of how virtual patient data is revolutionising paediatric clinical trials. In our upcoming episode, we delve into groundbreaking research that addresses one of h...

30 Juni 202528min

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

Beyond the Scalpel: How Computer Models Are Rewriting Paediatric Heart Surgery

This episode explores groundbreaking research from Boston Children's Hospital and Harvard Medical School that demonstrates how multiphysiologic state computational fluid dynamics (CFD) modelling is tr...

23 Juni 202522min

Future-Proofing the UK Life Sciences Sector

Future-Proofing the UK Life Sciences Sector

Are you prepared for the seismic shift transforming UK life sciences careers? This latest "In Silico Trials, Real Impacts!" episode reveals how AI and in silico technologies are creating unprecedented...

16 Juni 202517min

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Exploring the Limitations and Potentials of RCTs: Beyond the Gold Standard

Are Randomised Controlled Trials (RCTs) always the definitive 'gold standard' in research? In the latest episode of In Silico Trials, Real Impacts!, we explore the nuanced landscape of RCTs, questioni...

9 Juni 202532min

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Simpler or Complex: Rethinking Occam's Razor in Modelling Science

Is simplicity always the smartest choice in science? Or could complexity be the key to groundbreaking discoveries? This episode explores the evolving role of simplicity and complexity in scientific mo...

2 Juni 202527min

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Evaluating Continuous Glucose Monitoring Sensors with in Silico Trials: A Real-World Exemplar

Could computer simulations redefine diabetes care? In this episode, we focus on a real medical product and the role of in silico trials in the transition from the Medtronic Guardian Sensor 3 to the Gu...

25 Maj 202515min

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance o...

19 Maj 202516min

What Underpins Model Credibility? Three Philosophical Perspectives

What Underpins Model Credibility? Three Philosophical Perspectives

How do philosophers of science think about model evaluation? Dive deep into the crucial process of model evaluation, a fundamental step in digital science that determines the effectiveness and precisi...

12 Maj 202519min

Populärt inom Vetenskap

p3-dystopia
dumma-manniskor
allt-du-velat-veta
medicinvetarna
svd-nyhetsartiklar
sexet
rss-kriminologerna
kapitalet-en-podd-om-ekonomi
rss-ufobortom-rimligt-tvivel
bildningspodden
dumforklarat
rss-vetenskapsradion-2
det-morka-psyket
paranormalt-med-caroline-giertz
halsorevolutionen
rss-broccolipodden-en-podcast-som-inte-handlar-om-broccoli
vetenskapsradion
pojkmottagningen
rss-odla
rss-spraket