Nature Podcast10 Maj 2023

‘Pangenome’ aims to capture the breadth of human diversity

In this episode:

00:45 Making a more diverse human genome

The first draft of the human genome ushered in a new era of genetics research. Since its publication, researchers have constructed ever more accurate ‘reference genomes’ – baselines against which others are compared. But these are based on the DNA of a small number of people, and don’t represent the genetic variation known to exist across human populations. To address this, a consortium of researchers have published the first draft of a ‘pangenome’, which combines the genomes of 47 genetically diverse individuals. This draft provides a more complete picture of the human genome, and is the starting point for a project that aims to include sequences from 350 individuals.

Research article: Liao et al.

Research article: Vollger et al.

Research article: Guarracino et al.

News and Views Forum: Human pangenome supports analysis of complex genomic regions

08:33 Research Highlights

A wearable sensor that lets users see infrared light, and how a vulture’s culture can influence its dining habits.

Research Highlight: Wearable sensor gives a glimpse of ‘invisible’ light

Research Highlight: What drives a scavenger’s diet? Vulture culture

11:06 Briefing Chat

We discuss some highlights from the Nature Briefing. This time, a new phosphate-storing organelle found in fruit fly cells, and how extracted DNA revealed who held a deer-tooth pendant 20,000 years ago.

Nature News: New cellular ‘organelle’ discovered inside fruit-fly intestines

Nature News: Prehistoric pendant’s DNA reveals the person who held it

Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.

Hosted on Acast. See acast.com/privacy for more information.

Det här avsnittet är hämtat från ett öppet RSS-flöde och publiceras inte av Podme. Det kan innehålla reklam.

Avsnitt(926)

Briefing Chat: The Bunsen burner myth that turns out to be just hot air

Nature staff discuss an AI tool that can assess the impact of nine billion mutations — plus, how the Bunsen burner’s reputation for sterilization may be based on tradition alone.00:21 Deepmind’s new t...

11 Sep 15min

Phone tutoring boosts math scores when schools are forced to close

In this episode:00:46 How telephone teaching could boost education during school shutdownsNature: Pick up the phone! Phone calls with tutors keep kids learning when schools shut down11:42 Research Hig...

9 Sep 21min

Briefing Chat: How 1,000 pairs of buried underpants helped measure soil health

In this episode:00:21 Our picks of this year’s Ig Nobel prizesNature: Buried underpants and a new definition of kissing win 2026 Ig Nobel prizes07:47 Massive xenon experiment detects tantalizing hint ...

4 Sep 12min

Audio long read: Could mending damaged DNA prolong life?

Scientists are amassing evidence that unrepaired or poorly repaired DNA damage underlies many of the hallmarks of ageing. This has led to research into whether boosting DNA repair can keep people heal...

2 Sep 18min

Briefing Chat: How Dolly Parton left her mark on science

In this episode:00:18 Researchers celebrate Dolly Parton's contributions to scienceNature: Dolly Parton dies aged 80 — researchers celebrate her contributions to science08:40 Phase III trial of melano...

28 Aug 14min

Highest-ever ocean temperatures recorded as El Niño intensifies

Why extreme temperatures are expected to weaken ocean carbon sinks — plus, how mitochondrial injections could treat vision loss.00:46 The world’s oceans reach a record temperatureNature: Ocean tempera...

26 Aug 19min

Briefing Chat: New narcolepsy drug could unlock host of novel brain therapies

Nature staff discuss how an FDA-approved drug for narcolepsy could have promise beyond the condition, and the longest-lived human brain organoids yet.00:28 The promise of a new narcolepsy drugNature: ...

21 Aug 12min

A black hole's spin could finally be measured by a high-speed star

Star orbiting close to Sagittarius A* could reveal its spin — plus, how exoskeletons might change the way humans move.00:46 The star that could reveal a black hole’s spinResearch article: Dayem et al....

19 Aug 29min