What Drives Muscle Growth & What Doesn't | Dr. Mike Roberts

What Drives Muscle Growth & What Doesn't | Dr. Mike Roberts

In this episode, I sit down with Dr. Mike Roberts, Professor in the School of Kinesiology at Auburn University, and one of the most respected muscle physiologists, to explain how muscle actually grows. Mike shares that mechanical tension—not hormones, metabolic byproducts, or muscle damage—is the primary driver of hypertrophy. We cover why testosterone and androgen receptors don't necessarily predict muscle growth, what separates high responders from low responders, and how these “low responders” should train to best get results. We also work through training volume, load versus reps, lengthened partials, aging and anabolic resistance, and the interference effect between strength and endurance training. If you want to understand the real science of building muscle, this conversation is for you. Sponsors Momentous: https://livemomentous.com/galpin LMNT: https://drinklmnt.com/perform Trumed: https://truemed.com/perform Chapters (00:00:00) Introduction (00:03:15) How Muscle Grows (00:17:39) What Drives Growth: Tension, Stress & Damage (00:24:08) Responders vs. Non-Responders (00:29:54) Hormones, Receptors & Genetics (00:48:01) Cell Signaling, mTOR & Myostatin (00:56:32) Can Some People Not Grow Muscle? (01:01:34) Training Volume for Hypertrophy (01:08:34) Loads, Reps & Stretch Under Load (01:17:13) Range of Motion, Partials & Hyperplasia (01:31:31) Injury, Unloading & Muscle Banking (01:39:32) Muscle Memory: Detraining & Retraining (01:47:42) Aging, Menopause & Anabolic Resistance (02:01:21) Concurrent Training & the Interference Effect (02:08:54) How to Combine Strength & Cardio (02:24:03) Strength Training & Mitochondria (02:25:21) Closing Thoughts Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

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The Fundamentals of Nutrition, Hydration & Performance Fueling

The Fundamentals of Nutrition, Hydration & Performance Fueling

In this episode, I answer your questions on nutrition, hydration, and recovery in our second audience Q&A. I start with what I call the 90%: the principles nearly every effective nutrition plan shares...

5 Aug 1h 8min

The Fundamentals of Training for Muscle, Strength & Longevity

The Fundamentals of Training for Muscle, Strength & Longevity

In this episode, I answer your questions in the first-ever open Q&A on Perform, working through the five themes that came up most. I start with how I think about training for longevity—why being well-...

22 Juli 1h 12min

Identify & Fix Muscle Imbalances & Injury Risks 

Identify & Fix Muscle Imbalances & Injury Risks 

In this episode, I tackle muscle asymmetries and imbalances — when the differences between your two sides help you, when they hurt you, and what to actually do about them. I move past the popular "10%...

24 Juni 1h 39min

Female Training, Hormones & Nutrition: Fact vs. Fiction | Dr. Lauren Colenso-Semple

Female Training, Hormones & Nutrition: Fact vs. Fiction | Dr. Lauren Colenso-Semple

In this episode, I sit down with Dr. Lauren Colenso-Semple to examine what the science says about female-specific training and nutrition. We discuss why so little research has historically focused on ...

10 Juni 2h 8min

How to Think Clearly in an Age of Distraction | Sam Harris

How to Think Clearly in an Age of Distraction | Sam Harris

In this episode, I sit down with Dr. Sam Harris to discuss how attention, mindfulness, and clear thinking shape performance. We start by separating intelligence from wisdom, then look at how modern te...

27 Maj 2h 28min

Intense Exercise & Potential Heart Damage (aka Athlete's Heart)

Intense Exercise & Potential Heart Damage (aka Athlete's Heart)

In this episode, I cover "athlete's heart" — the paradox where the same cardiovascular adaptations that make endurance athletes exceptional can also mimic, and sometimes mask, real risk. I trace the h...

13 Maj 1h 44min

Hardship, Resilience & Competing at the Highest Level | Ken Rideout

Hardship, Resilience & Competing at the Highest Level | Ken Rideout

In this episode, I sit down with Ken Rideout — author, elite masters marathoner, and one of the most compelling people I've ever had on the show — to discuss his journey from a difficult childhood and...

29 Apr 2h 34min

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