Declining ALS Patients Are Waiting On The FDA's Next Move
Big Take23 Dec 2022

Declining ALS Patients Are Waiting On The FDA's Next Move

For many years, pharmaceutical companies have tried and failed to find a treatment to slow symptoms of ALS–the debilitating, fatal illness also known as Lou Gehrig’s Disease. A potentially promising new drug from Biogen may offer some relief to those afflicted with an uncommon and especially insidious form of ALS that runs in families. Patients are urging the US Food and Drug Administration to speed access to the drug, which hasn’t yet been approved because clinical trials didn’t conclusively show it works.

As pharmaceutical companies use new technologies to seek cures of all kinds, this tension between making sure drugs are effective and safe, and offering not-quite-ready but possibly life-saving treatment to people for whom it’s now or never, is becoming more acute.

Bloomberg’s chief medical writer Robert Langreth joins this episode to talk about the race to find a treatment for ALS–and the back and forth between patients, companies and government regulators. We also hear the story of a Pennsylvania family that has passed on a gene for ALS from generation to generation–and their demands for access to the new treatment.

Learn more about the episode here: https://bloom.bg/3WIkvCm

Listen to The Big Take podcast every weekday and subscribe to our daily newsletter: https://bloom.bg/3F3EJAK

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Clash of the Streaming Titans

Clash of the Streaming Titans

Remember when everyone loved to complain how there were 150 channels on TV and nothing good to watch? It’s pretty hard to say that now. There are so many good shows being made. Our new complaint: how hard it is to watch all those great shows, especially when they’re spread across so many streaming services—and most of them you have to pay for. How did we get here?  Bloomberg media reporter Felix Gillette has answers.  He’s the co-author of the upcoming book It's Not TV: The Spectacular Rise, Revolution, and Future of HBO.Felix joins this episode to break down why TV has never been better–and yet has never been more frustrating to watch.  Bloomberg’s entertainment reporter Lucas Shaw also stops in to explain how this shift has changed the way Hollywood decides which shows get made--and which ones don't.Read the Book excerpt here: https://bloom.bg/3SI08CA Listen to The Big Take podcast every weekday and subscribe to our daily newsletter: https://bloom.bg/3F3EJAK  Have questions or comments for Wes and the team? Reach us at bigtake@bloomberg.net.See omnystudio.com/listener for privacy information.

28 Okt 202229min

The US Middle Class Is Doing Fine. Why Are They So Worried?

The US Middle Class Is Doing Fine. Why Are They So Worried?

Hello and welcome to The Big Take Podcast! Today: The good news, and not so good news, about the US middle class. With inflation rising, the stock market ping-ponging and housing prices softening, that broad swath of Americans who form the backbone of the US economy are getting hit on all sides. Bloomberg reporters Shawn Donnan, Alex Tanzi, Claire Ballentine and Airielle Lowe teamed up to take a look at how middle-income Americans are doing. The answer: Not so badly, actually–at least on paper. Even so, they’re worried about what’s next for them. And they have good reason to be. Shawn sits down with Wes to share the results from their exclusive polling and what these precarious economic times mean for the fortunes of working Americans. Learn more about this story here: https://bloom.bg/3faCxwM Listen to The Big Take podcast every weekday and subscribe to our daily newsletter: https://bloom.bg/3F3EJAK  Have questions or comments for Wes and the team? Reach us at bigtake@bloomberg.net.See omnystudio.com/listener for privacy information.

27 Okt 202229min

Introducing: The Big Take

Introducing: The Big Take

Each weekday, The Big Take brings you one story—one big, important story that impacts your life. Host Wes Kosova talks to Bloomberg journalists around the world, experts in their fields and the people at the center of the news to help you understand what’s happening, what it means and why it matters. Money, politics, the economy and business, energy, the environment, technology—we cover it all on The Big Take. And we do it in plain English. The Big Take features the best of Bloomberg's in-depth, original reporting from around the globe. Listen each weekday starting on Oct. 27. Learn more about The Big Take www.bloomberg.com/bigtake and subscribe to our daily newsletter https://bloom.bg/3rBmR9g.See omnystudio.com/listener for privacy information.

19 Okt 20222min

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