1005: David Fajgenbaum | Leveraging AI to Cure Rare Diseases

Amanda Knox (@amandaknox) is an exoneree, journalist, public speaker, and author of Waiting to Be Heard. She was the host of The Scarlet Letter Reports and currently co-hosts The Truth About True Crime podcast. What We Discuss with Amanda Knox: How Amanda was coerced into wrongfully confessing that she was at the scene of her roommate's murder without being made aware of her rights or being given access to a lawyer. Why not understanding the difference between being questioned as a witness and interrogated as a suspect landed Amanda in custody for 1,428 days without being allowed to see her family. How even a false confession, once made, often sways a jury to convict a defendant before any of the evidence is even considered, and why it's not uncommon for a completely innocent person to give a false confession to a skilled interrogator looking to close a case quickly. Why a police department investigating a case under the scrutiny of a worldwide media frenzy might be less interested in carrying out justice than covering up its own countless acts of gross incompetence. Why a populace literate in its own legal rights is the only real way to combat the manipulation of ignorance -- by both prosecution and defense -- in the court system that leads to so many wrong outcomes. And much more... Full show notes and resources can be found here: jordanharbinger.com/386 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Aug 20201h 25min

While googling someone you met on a dating app, it turns out they have a white-collar criminal record. Should you give them the benefit of the doubt that they've learned from their mistake, or back off now? We'll tackle this and more here on Feedback Friday! And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in! Full show notes and resources can be found here: jordanharbinger.com/385 On This Week's Feedback Friday, We Discuss: While googling someone you met on a dating app, it turns out they have a criminal record for intellectual property theft. Should you give them the benefit of the doubt that they've learned from their mistake, or back off now? How can you get clients and colleagues to take you seriously as a professional when you look much younger than your years? How do you deal with the envy and resentment you feel toward a friend who is doing miles better than you in their career even though you both started at the same time? Thanks to the pandemic, the job you were supposed to start in August has been pushed to begin in January. What can you do between now and then to make sure it's still there when the new year rolls around? You've been a nurse in a COVID unit for five months, and your friends and family are terrified to be near you. It might be tolerable if you had a significant other for support, but you're single and the loneliness is unbearable. What can you do? You're currently in the "Gmail Roulette" part of Six-Minute Networking, and the success rate has been excellent. However, how do you manage to avoid being overwhelmed by all the incoming traffic? Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com! Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger. Connect with Gabriel on Twitter at @GabeMizrahi. And if you want to keep in touch with former co-host and JHS family Jason, find him on Twitter at @jpdef and Instagram at @JPD, and check out his other show: Grumpy Old Geeks. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

31 Juli 202042min

Aimen Dean (@AimenDean) was once one of al-Qaeda’s most respected bomb-makers who swore allegiance to Osama bin Laden himself. He eventually switched sides and spent eight years as an MI6 spy trying to take al-Qaeda down from the inside. He is the author of Nine Lives: My Time as the MI6’s Top Spy Inside Al-Qaeda and co-host of podcast Conflicted. This is part one of a two-part episode that will conclude later this week! What We Discuss with Aimen Dean: The radicalizing circumstances that contributed to Aimen's recruitment by Islamic extremists after memorizing the Quran by age 12. Early misgivings about the cause brought about by witnessing a brutal revenge massacre instigated by his own side during the Bosnian War when he was only 17. What Aimen learned about "logistical back-office jihad" and financing terrorism on a global scale while creatively accounting for a now-infamous charity front. Aimen's trip to Afghanistan at the behest of 9/11 mastermind Khalid Sheikh Mohammed that led him to swear allegiance to Osama bin Laden and Al-Qaeda. What Aimen learned -- and taught -- about ingenious and terrible methods of torture that would extract confessions from victims without leaving permanent marks. And much more... Full show notes and resources can be found here: jordanharbinger.com/384 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Juli 20201h 23min

Aimen Dean (@AimenDean) was once one of al-Qaeda’s most respected bomb-makers who swore allegiance to Osama bin Laden himself. He eventually switched sides and spent eight years as an MI6 spy trying to take al-Qaeda down from the inside. He is the author of Nine Lives: My Time as the MI6’s Top Spy Inside Al-Qaeda and co-host of podcast Conflicted. This is part one of a two-part episode that will conclude later this week! What We Discuss with Aimen Dean: The radicalizing circumstances that contributed to Aimen's recruitment by Islamic extremists after memorizing the Quran by age 12. Early misgivings about the cause brought about by witnessing a brutal revenge massacre instigated by his own side during the Bosnian War when he was only 17. What Aimen learned about "logistical back-office jihad" and financing terrorism on a global scale while creatively accounting for a now-infamous charity front. Aimen's trip to Afghanistan at the behest of 9/11 mastermind Khalid Sheikh Mohammed that led him to swear allegiance to Osama bin Laden and Al-Qaeda. What Aimen learned -- and taught -- about ingenious and terrible methods of torture that would extract confessions from victims without leaving permanent marks. And much more... Full show notes and resources can be found here: jordanharbinger.com/383 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

28 Juli 20201h 25min

You and the spouse moved in with your father-in-law to emotionally support him when your mother-in-law passed away, but it's difficult to relax or work from home on a foldout bed in the dining room. How can you bring up the subject of bowing out to another (nearby) place -- by yourself for the time being if necessary -- without feeling insensitive? We'll try to help you out with this and more here on Feedback Friday! And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in! On This Week's Feedback Friday, We Discuss: "A practical definition of opportunity cost: If you spend too much time working on good things, then you don’t have much time left to work on great things." -James Clear You and the spouse moved in with your father-in-law to emotionally support him when your mother-in-law passed away, but it's difficult to relax or work from home on a foldout bed in the dining room. How can you bring up the subject of finding another (nearby) place without feeling insensitive? When reconnecting with people you've lost touch with for ages, how can you diplomatically ask for exactly what you're looking for without sounding like a user or opportunist? Is your reluctance to take on a new job that would pay you four times more than you've ever made before due to legitimate concerns over your own competence, or are you just suffering from pangs of imposter syndrome? You lent a friend $63k on your credit card, and it's now clear you'll never see that money again. Even worse, you're stuck with the bill and can't even cover minimum payments. You could consolidate your debt or file for bankruptcy -- but are these really your only options? Working from home during quarantine made you realize you like being more present for your kids than commuting an hour each way to the office -- which the boss wants you to start doing again now that the state has decreed things "safe." Are you crazy for wanting to start your own business in these uncertain times? Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com! Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger. Connect with Gabriel on Twitter at @GabeMizrahi. And if you want to keep in touch with former co-host and JHS family Jason, find him on Twitter at @jpdef and Instagram at  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Juli 202047min

Neal Brennan (@nealbrennan) is a comedy writer/producer/director, co-creator of Chappelle's Show, host of the How Neal Feel podcast, and is featured in his own live standup solo show 3 Mics at Netflix. What We Discuss with Neal Brennan: How Neal's 3 Mics show came about, and the idea behind its three parts: one-liners, emotional stuff, and stand up. The comedy-writing process and how it mirrors real life. A mindset to get a more realistic handle on the potential outcome of a given project or situation. Tips on getting happy from a guy who's tried everything -- and why achievement can't be a substitute for happiness. When networking, remember Neal's sage words: "No one's going to help you in a way that's not beneficial to them." And so much more... Full show notes and resources can be found here: jordanharbinger.com/381 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Juli 202054min

Blake Mycoskie (@BlakeMycoskie) is the philanthropic founder of TOMS Shoes, author of Start Something That Matters, and co-founder of wellness subscription box service Madefor (get 20 percent off by using code MFJORDAN if you feel like checking it out). What We Discuss with Blake Mycoskie: What Blake's new Madefor startup can do to make you better (and how you can get 20 percent off by using code MFJORDAN if you feel like checking it out). Why entrepreneurship is more than just saying "I don't want a boss" -- it's seeking to remedy a problem the world needs to have solved. The benefits of cultivating the "beginner's mind" of a Buddhist. Why Blake advises founders in the early stages of a startup to bootstrap resources rather than seek investment dollars. What Blake sees as emerging business trends in a COVID-19 world and beyond. And much more... Full show notes and resources can be found here: jordanharbinger.com/380 Sign up for Six-Minute Networking -- our free networking and relationship development mini course -- at jordanharbinger.com/course! Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter handle so we can thank you personally!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

21 Juli 202057min

You know that your father, who has a history of cheating on your mother, is currently having an affair with a family "friend." How should you deal with your cheating dad in a way that won't destroy what little cohesion your family has left? We'll tackle this and more here on Feedback Friday! And in case you didn't already know it, Jordan Harbinger (@JordanHarbinger) and Gabriel Mizrahi (@GabeMizrahi) banter and take your comments and questions for Feedback Friday right here every week! If you want us to answer your question, register your feedback, or tell your story on one of our upcoming weekly Feedback Friday episodes, drop us a line at friday@jordanharbinger.com. Now let's dive in! Full show notes and resources can be found here: jordanharbinger.com/379 On This Week's Feedback Friday, We Discuss: You know that your father, who has a history of cheating on your mother, is currently having an affair with a family "friend." How should you deal with your cheating dad in a way that won't destroy what little cohesion your family has left? How can you keep growing your side hustle that has thrived during quarantine while convincing your unreasonable full-time boss that both of you would be happiest if you took a part-time consulting role so you don't lose your stake in the company? You find your workshop job well-paying and satisfying, but it takes its toll on your body -- as evidenced by your older coworkers. How can you secure an office job at your company to avoid the same fate? You've developed skills for finding and acting on opportunities that you'd like to share with others, but potential mentees so far have been lacking in ambition. How can you teach them to fish when they just expect the fish to come to them? Life Pro Tip: If you're a DJ, music producer, or podcast audio engineer, software can get pretty expensive. Email software companies explaining that you love their product and you want to do the right thing by legally purchasing it, but money is tight. They're often willing to pass along deep discounts when possible. Have any questions, comments, or stories you'd like to share with us? Drop us a line at friday@jordanharbinger.com! Connect with Jordan on Twitter at @JordanHarbinger and Instagram at @jordanharbinger. Connect with Gabriel on Twitter at @GabeMizrahi. And if you want to keep in touch with former co-host and JHS family Jason, find him on Twitter at @jpdef and Instagram at @JPD, and check out his other show: Grumpy Old Geeks. Sign...See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Juli 202043min